Chapter 10 - Chromosomes, Mitosis, and Meiosis Flashcards
Chromosomes
major carriers of genetic information in eukaryotes
histones
proteins that facilitate chromosome packaging
nucleosomes
structure consisting of eight histone molecules and DNA wrapped around it
scaffolding proteins
nonhistone proteins that help maintian chromosome structure
phases in cell cycle
interphase and m phase
phases within interphase
G1, S, and G2
What takes place in G1 phase?
Growth and normal metabolism. Towards end of this phase, enzymes required for DNA synthesis become more active. Synthesis of these enzymes enables cell to enter S phase
What takes place in S phase?
DNA replicates and histone proteins are synthesized so that the cell can make duplicate copes of its chromosomes
What takes place in G2 phase?
increased protein synthesis
G1-S Checkpoint
ensures that cell has necessary growth factors, nutrients, and enzymes to synthesize DNA
Metaphase-anaphase checkpoint (spindle checkpoint)
Prevents anaphase from occurring until all kinetochores are properly attached to spindle fibers along the cell’s midplane
G2-M Checkpoint
ensures that DNA replication is finished BEFORE cell begins mitosis