Chapter 12 Blood Flashcards
What factors affect blood volume
Body size
Changes in fluid and electrolyte concentration
Amount of adipose tissue
Describe red blood cells
Biconcaved discs
What is the function of hemoglobin
It’s a protein found on the surface of red blood cells/ binds to oxygen
How does a red blood cell change as it matures?
It loses the nucleus
What is the typical red blood cell count for an adult male and for an adult female.
For males it’s 4,600,000 to 6,200,000 cells per microliter for females it’s 4,200,000 to 5,400,000 cells per microliter.
Where are red blood cells produced?
In the red bone marrow
How is red blood cell production controlled?
Low blood oxygen stimulates the liver and kidney which releases erythropoietin into the bloodstream and stimulates the red bone marrow to increase the number of red blood cells.
Which vitamins are necessary for red blood cell production.
Vitamin B 12 and folic acid as well as iron.
Why is iron required for the formation of red blood cells
I think it’s because it’s necessary for protein synthesis but really I’m just making that up
What happens to damaged red blood cells
Macrophages phagocytize and destroy damaged red blood cells primarily in the liver and spleen; hemoglobin molecules break down into biliverdin and then into bilirubin. Biliverdin and bilirubin are excreted in the bile as pigment.
What are the products of hemoglobin breakdown
Biliverdin and bilirubin
Which hormones are necessary for differentiation of white blood cells from hemopoietic stem cells in the red bone marrow
Interleukins and colony stimulating factors
Distinguish between granulocytes in agranulocytes
Granulocytes are granulated and agranulocytes are not granulated
List the five types of white blood cells and explain how they differ from one another
Neutrophils,eosinophils, and basophils are granulated. Neutrophils are light purple and have multi lobed neuclei. Eosinophils appear deep red and have bilobed neuclei. Basofils appear blue.
Monocytes and lymphocytes are agranulated. Monocytes are the largest blood cells their nuclei vary in shape. Lymphocytes are only slightly larger than red blood cells and have a round nucleus which takes up most of the cell.
How do white blood cells to fight infection
Through Phagocytosis and producing antibodies
How do you white blood cells reach micro organisms that are outside blood vessels
Monocytes leave blood vessels and become macrophages.
Which white blood cells are the most active phagocytes
Monocytes and neutrophils