Chapter 11 PH Regulation Flashcards
True or false.
For every crossbridge performed there has to be an ATP that is hydrolyzed to cock the myosin head.
True
What does acidosis mean and the relation it has to hydrogen?
Acidosis is when the PH goes below 7.35, and it relates to hydrogen because when there is an accumulation of hydrogen in the muscles this causes the local area to reduce PH levels leading to Acidosis.
True or false.
Insulin is needed by every cell in the body to get glucose inside including skeletal muscle.
False, Skeletal muscle is the only cell that does not need insulin to allow glucose to enter inside its cell.
What happens to glucose uptake as exercise intensity increases?
Glucose uptake will increase as exercise intensity rises because of the unique ability to allow glucose to enter the cell without insulin to target the delivery of glucose to actual working muscle sites.
What is the significance of having an increase of glucose uptake during exercising and glycolysis?
The increase of glucose delivery to active cells that causes more ATP hydrolysis of converting glucose to glucose-6-phosphate for glycolysis.
What is the relationship between PH and hydrogen concentration?
An inverse relationship between PH and Hydrogen concentration where low PH means high H+ concentration and vise versa.
Where does hydrogen come from primarily and the source of it during exercise?
Hydrogen comes muscle contractions through the sliding filament theory and the source of it is from ATP hydrolysis within the sliding filament theory.
True or false.
An increased contraction rate of a muscle does not influence the concentration of hydrogen.
False, increased contraction rate will cause an increase in hydrogen concentration.
How does lactate move around the body and what does it co-transport?
Through monocarboxylate transport 1 or 4.
Hydrogen
Fill in the Blanks.
The movement of lactate around the body is facilitated by ___________ which carries lactate outside the cell. Where ___________ carries lactate _________ the cell.
MCT 4 (Monocarboxylate Transport)
MCT 1
Inside
What is Cystolic LDH Deficiency and how does this affect people working out?
Cystolic LDH deficiency is a genetic disorder where the levels of LDH are lower than a normal person.
This means that when someone with cystolic LDH deficiency cannot work and maintain the same intensity as a normal person. This also means that they cannot exercise for long periods nor can do moderate to vigorous exercise efficiently. This can lead to rhabdomyolysis and apoptosis.
