Chapter 11 - Cerebral Asymmetry Flashcards
What does the term laterality indicate?
- The idea that the hemispheres have distinct functions (and structure)
What’s considered the general laterality between the left and right hemispheres in the human brain?
- Left: producing and understanding language
- Right: Perceiving and synthesizing nonverbal information such as music and facial information, and spatial stuff
What are some variables to consider when discussing laterality?
- Laterality is relative, not absolute (ex. right hemisphere can still have language capabilities)
- Cerebral site is at least as important in understanding brain function as cerebral side
- Environmental and genetic factors affect laterality
- A range of animals exhibit laterality
- We act as though there is a single side
T/F: The right thalamus is larger.
- FALSE
- The left thalamus is larger
Wernicke’s area is larger in which side?
- The left hemisphere
- It specializes in language
Heschl’s gyrus is larger in which side?
- The right hemisphere
- It’s another name for the primary auditory cortex
The lateral fissure has a steeper slope on which side?
- The right side
What are the 8 major anatomical differences between hemispheres?
- Right side is slightly larger and heavier, but left has higher grey: white matter ratio
- Structural asymmetry in temporal lobes likely corresponds to functional difference
- Thalamic asymmetry
- Steeper lateral fissure on right side
- The frontal operculum (part of broca’s area in left hemi) is a larger area buried in sulci (grammar production) while it’s a larger area visible on the surface of the right side (tone of voice?)
- Asymmetric distribution of neurotransmitters in both cortical and subcortical regions
- Right side extends farther anteriorly, left extends farther posteriorly (cerebral torque/Yakolevian torque)
- Thicker cortex in left side, larger surface area in right side, regionally specific asymmetries in 31/34 regions
What’s considered the strongest evidence for studying lateralization?
- Double dissociation methodologies
What’s double dissociation?
- An experimental technique by which 2 neocortical areas are functionally dissociated by two behavioural tests
- Performance on each is affected by a lesion in one area, but not the other
- Demonstrates lateralization and localization
What’s an example of a double dissociation?
- Patient 1: Lesion to A affects function X, but not function Y; Patient 2: Lesion to B affects function Y, but not X
Generally, what functions do the left and right hemispheres specialize in?
- Left: Langauge and speech comprehension
- Right: Spatial navigation and music.
Commissurotomy vs. Callostomy?
- Commissurotomy - When all commissures in the brain have been surgically severed
- Callostomy - Only the corpus callosum is severed
What are the major effects of a commissurotomy on interhemishperic connections?
- Sensory info can be presented to one hemisphere in isolation
- Functions can then be studied without the other hemisphere having access to that information
What’s a general overview of the visual pathway from the eyes to the brain?
1) Light hits the retina
2) Signals travel down the optic nerve to the optic chiasm
3) 50% of signals transfer at the chiasm, info continues down the optic tract
4) Info reaches the LGN in thalamus, then follows the optic radiation
5) Info reaches V1 and is processed subsequently
T/F: Visual input from the left hemifield is processed in the left hemisphere, and info from the right hemifield is processed in the right hemisphere.
- FALSE
- Visual systems are crossed, therefore visual info from the left hemifield is processed in the right hemisphere and so forth.
Nasal retina vs. temporal retina?
- Temporal retina - visual info remains ipsilateral
- Nasal retina - visual info is contralateral