Chapter 11

Question 1

Gyrase

Answer 1

-The enzyme that moves ahead of each replication fork to remove the supercoiling caused by the unwinding of the two polynucelotide strands

Question 2

Single- stranded binding proteins

Answer 2

These protein maintain the unwound state of the two polynucleotide strands at the replication fork.

Question 3

DNA polymerase

Answer 3

The enzyme that removes the RNA primer and fills in the gap with DNA

Question 4

Primase

Answer 4

• The enzyme that makes a short RNA during replication

- The enzyme that creates a phosphodiester bond between 2 ribonucleotides

Question 5

DNA Ligase

Answer 5

This enzyme forms the phosphodiester bond between two adjacent polynucleotide strands; it primarily functions on the lagging strand to join okazaki fragment together.

Question 6

Telomerase

Answer 6

The enzyme/RNA complex that is involved in replicating the ends of a linear chromosome

Question 7

Replication Fork

Answer 7

The location of replication within the replication bubble

Question 8

Tandem repeat

Answer 8

This feature of a telomere binds to the RNA of telomerase

Question 9

3’ overhang

Answer 9

The single-stranded DNA region in the telomere

Question 10

Deoxyribonucleotide

Answer 10

The Substrate that DNA polymerase uses to make a phosphodiester bond with the 3’OH on the end of the newly synthesizing strand.

Question 11

TERT

Answer 11

The enzyme that makes DNA from RNA at the ends of the chromosomes during replication

Question 12

Origin of replication

Answer 12

The location on the DNA where helicase first binds to create the replication bubble

Question 13

Chromatin

Answer 13

This is the generic word for DNA bond with protein; interphase DNA.

Question 14

Ribonucleotides

Answer 14

The substrate of primase