Chapter 11 Flashcards

1
Q

What were the findings regarding a study showing the adoption of children whose mothers were hospitalized for schizophrenia?

A

Kids were shown to have an increased chance of developing schizophrenia and schizophrenia-related disorders despite being adopted.

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2
Q

What does the Dopamine Hypothesis entail?

A

For: Drugs that are effective in treating schizophrenia decrease dopamine activity. Amphetamines may introduce symptoms of psychosis that resemble paranoid schizophrenia.

Against: oversensitive dopamine receptors.

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3
Q

What is serotonin?

A

Regulate dopamine neurons in the mesolimbic pathway

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4
Q

What is glutamate?

A

Play roles in brain function, including learning and memory. Low levels of glutamate are found in ppl w/ schizophrenia.

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5
Q

What are Congenital & Development Considerations concerning schizophrenia?

A

(1) Viral infection (no real evidence)
(2) Rhesus Incompatibility
(3) Pregnancy & Birth Complications
(4) Early Nutritional Deficiency
(5) Maternal Stress
(6) Gene & Environmental Synthesis

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6
Q

How does stress affect schizophrenia?

A

Increase in life stress → increase in likelihood of relapse
Increased rates of schizophrenia found in central city areas w/ low socio-economic status

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7
Q

What is the Sociogenic Hypothesis regarding schizophrenia

A

Stressors associated w/ being in a low social class may cause or contribute to development of schizophrenia

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8
Q

What is Social-Selection Theory?

A

During the course of their developing psychosis, people with schizophrenia may drift into the poverty-ridden areas of the city.
May move to areas with little social pressure to escape intense social relationships.

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9
Q

What is Schizophrenia?

A

Disorder characterized by psychosis.
Characterized by Disordered thinking (ideas not logically related), Faulty perception and attention, Inappropriate affect, Bizarre disturbances in motor activity

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10
Q

What is the prevalence & comorbidity of schizophrenia?

A

Prevalence
Appears in late ado or early adulthood
Occurs in episodes w/ less severe symptoms in between
Appears earlier in men

Comorbidity
Substance abuse, depression, social anxiety

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11
Q

What are the positive symptoms of schizophrenia?

A

Positive: presence of too much of a behaviour that isn’t apparent in most ppl

(1) Disorganized Speech: fails to make sense, incoherence, neologisms
(2) Delusions: erroneous belief firmly held, despite contradictory evidence
(3) Hallucinations: Sensory experience, feels real, but isn’t. More auditory

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12
Q

What are the negative symptoms of schizophrenia?

A

Negative: absence of a behaviour that should be evident in most ppl

(1) Reduced Expressive behaviour:
Flat affect: no facial/ emotional response. No stimulus can elicit a response
Alogia: poverty in speech/ content of speech

(2) Reductions in motivation:
Avolition: inability to initiate/ persist in goal-directed activity. Lack of interest
Anhedonia: Diminished ability to experience pleasure
Asociality: Severely impaired social relationships (few friends, poor social skills, etc.)

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13
Q

What is Catatonia?

A

A class of symptoms of schizophrenia. Includes:
(1) Several motor abnormalities: Appears similar to mania, gestures repeatedly, increase in activity
(2) Catatonic immobility: adoption of unusual postures and maintaining them for long periods

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14
Q

What is Disorganized Schizophrenia?

A

(1) Disorganized speech, disorganized behaviour & flat or inappropriate affect
(2) Hallucinations/ delusions (no theme)
(3) Early and gradual onset, poor prognosis

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15
Q

What is Catatonic schizophrenia?

A

(1) Marked by psychomotor disturbances
(2) Rare in industrialized countries

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16
Q

What is paranoid schizophrenia?

A

(1) Delusions/ frequent auditory hallucinations
(2) No disorganized speech, catatonic behaviour, or flat affect
(3) Good prognosis

17
Q

What is Undifferentiated schizophrenia?

A

Presence of symptoms, but not met for Paranoid, disorganized, or Catatonic type

18
Q

What is Residual schizophrenia?

A

When there has been at least one episode of schizophrenia but no longer prominent positive/ disorganized symptoms
Continued negative or attenuated positive symptoms

19
Q

What are the OUTDATED BIOLOGICAL treatments for schizophrenia?

A

Outdated Treatments
(1) Insulin Coma Therapy
(2) ECT
(3) Lobotomy
(4) Repetitive Transcranial Magnetic Stimulation

20
Q

What are the current BIOLOGICAL treatments for schizophrenia?

A

Antipsychotic Medication
(1) First gen:
Mainly effective on positive symptoms. Block dopamine receptors. Neuroleptic malignant syndrome
(2) Second gen:
Effective on positive and negative symptoms. Block broader range of receptors. Fewer side effects

21
Q

What is CBT?

A

(CBT) Changing negative thoughts and behaviours to improve mood and functioning

22
Q

What are the PSYCHOSOCIAL treatments for schizophrenia?

A

(1) Social Skills Training
Learning skills in specific domains (work, relationships, self-care)
Breaking down tasks easier
May not improve global functioning

(2) Family Therapy & Reducing Expressed Emotion
Working w/ patient’s family to improve communication, reduce stress, and address issues related to the illness