Chapter 10: Questions Flashcards
How are opioid analgesics characterized?
By mechanism of action (how they bind to receptors)
What would you treat opioid withdrawal with?
Benzodiazepines
What substances do opioids interact with?
Alcohol, antihistamines, barbiturates, benzodiazepines, & MAOI’s (antidepressants)
Fentanyl in a dose of 0.1mg IV is roughly equivalent to _____mg morphine IV?
10mg IV morphine = 0.1mg IV fentanyl
_____________ is approximately 7x more potent than morphine and is referred to dilaudid to avoid confusing with morphine.
HydromorPHONE
___________ hydrochloride must be used with caution, if at all. In older adults, those with kidney dysfunction, or long term use. This drug can accumulate to toxic levels and lead to ____________.
Meperidine hydrochloride can lead to seizures
Morphine is available in oral, rectal, injectable, and extended-release forms such as _______ & _________.
MS Contin & Kadian
_____________ hydrochloride is commonly combined in tablets with acetaminophen (Percocet) and with aspirin (percodan)
Oxycodone
__________ has a duel mechanism of action. It inhibits re-uptake of norepinephrine and serotonin, which is unique.
Tramadol
What should be assessed when giving buprenorphine and butorphanol?
Respirations before, during, and after use.
What should PO doses of codeine be given with?
Food
It is important to administer Parenteral doses of fentanyl over 1-2 minutes to prevent ____________, and possible ___________ or ______________.
To prevent: CNS depression and possible cardiac or respiratory arrest.
If pain cannon be managed by one medication (monotherapy), a combination of a variety of medication may be needed. List other drugs that can be included.
Anti anxiety, sedatives, hypnotics, anticonvulsants