3 Main components of DNA
Purine Ring system
aromatic 6 ring (2 N) attached to aromatic 5 ring (N and NH)
Pyrimidine ring
Aromatic 6 ring (2 N)
What happens when bases become charged?
they become soluble in water
Are bases soluble in water at pH 7?
NO (hydrophobic)
Bases can be charged at
very low or high pH
The double bond of bases absorb at
260 nm
Difference between RNA and DNA structure
2’ OH in DNA and 2’ H in RNA
Phosphate’s charge at physiological pH
negative
Nucleoside
Ribose + Base
Nucleotide
Ribose + Base + phosphate