Chapter 1 Quiz Flashcards
Which radionuclides are possible radioactive contaminants in the eluent of Rb82 generator?
-Sr82 and Sr 85
-Sr82 and Zr82
-Zr 82 and Zr85
-Sr82 and Sr87
Sr82 and Sr 85
Negative ion PET cyclotrons accelerate which of the following types of particles?
-Protons
-negatively charged hydrogen atoms
-negatively charge neutrons
-negatively charges protons
negatively charged hydrogen atoms
F18 labeled to glucose using a chemical method known as _____.
-electrophilic substitution
-base hydrolysis
-mannose triflate hydrolysis
-nucleophilic substitution
nucleophilic substitution
The bombarding particles used for the nuclear reactions that occur in a cyclotron must have an energy of at least ____MeV.
3
5
8
10
8
The most common irradiation process of producing F18 with a 109.7 minute half-life is ______.
O18 (p,alpha) F18
O16 (p,pn) F18
O16 (p,alpha) F18
O18 (p,n) F18
O18 (p,n) F18
According to the US federal regulations, any product with a half-life greater than ____ minutes must pass quality control testing before it can be released for human use.
10
20
30
60
20
As specified in the USP, F18-FDG must have chemical purity of greater than ____.
85%
90%
95%
98%
90%
Which of the following quality control tests for F18-FDG CANNOT be preformed before patient use?
radiochemical purity
radionuclidic purity
pH
sterility
sterility
The initial precursor molecule for producing F18-FDG is _____.
mannose triflate
dibutylboron triflate
trifluoroacetic acid
methyl triflate
mannose triflate
Because of the high amount of radioactivity, the production of PET radiopharmaceuticals must be done in lead-shielded hot cells and with an automated system called a ______.
cyclotron
synthesis module
reactor vessel
Kryptofix 222
synthesis module