Chapter 1 (Part 2) Flashcards
also called “plasmalemma”
▪ allows the cell to take up and retain certain substances while excluding others
plasma membrane
various _____ embedded in the plasma membrane are responsible for this
selective traffic of solutes across the membrane
transport proteins
delimit the boundaries of the specialized internal organelles of the cell and regulate the fluxes of ions and metabolites into and out of these compartments
Plasma Membrane
____ - class of lipids in which two fatty acids are covalently linked to
___, which is covalently linked to a ___ group; consequently, phospholipid
molecules display both hydrophilic and hydrophobic properties (i.e., they are
____)
phospholipids;
glycerol; phosphate;
amphipathic
fatty acids:
contains no double bonds= __
has one or more cis double bonds=___
saturated;
unsaturated
cis double bonds creates a ___in the chain that prevents tight packing
of the phospholipids in the bilayer; as a result, the ___of the membrane is
increased
kink;
fluidity
proteins associated with the lipid bilayer are of three types
integral
peripheral
anchored
____ - span the entire width of the phospholipid bilayer, so one part of the protein interacts with the ___ of the cell,
another part interacts with the ____ of the membrane, and a third part
interacts with the interior of the cell, the ____
integral proteins;
outside;
hydrophobic core;
cytosol
____- bound to
the membrane surface by noncovalent bonds, such as ionic bonds or hydrogen bonds, and can be dissociated from the membrane
peripheral proteins
break ionic bonds=
break hydrogen bonds=
high salt solutions;
chaotropic agents
____ - bound to the membrane surface via lipid molecules, to which they are ___attached.
anchored proteins;
covalently
the organelle that contains the genetic information primarily responsible for regulating
the metabolism, growth, and differentiation of the cell
nucleus
collectively, genes and their intervening sequences are referred to as the ____
nuclear genome
double membrane surrounding the nucleus
nuclear envelope
space between the two
membranes of the nuclear envelope is called the ____
perinuclear space
the two membranes of the nuclear envelope join at sites called _____
nuclear pores
nuclear “___”
is actually an elaborate structure composed of more than a hundred different proteins
arranged ____ to form a nuclear pore complex; central “plug” of the complex
acts as an _____ that facilitates the movement of
macromolecules and ribosomal subunits both into and out of the nucleus
pore; octagonally;
active (ATP-driven) transporter;
______- specific amino acid sequence; is required for a protein to gain entry into the nucleus
nuclear localization signal
DNA-protein complex is collectively known as ____
chromatin
___- densely granular region; site of ribosome synthesis
nucleolus
____– sites of protein synthesis
ribosomes
elaborate network of internal membranes
ER
membranes of the ER are typical lipid bilayers with interspersed ____and
____proteins; these membranes form flattened or tubular sacs known as
_____
integral and peripheral;
cisternae
____ - covered with ribosomes that are actively engaged in protein
synthesis; tends to be _____(a flat sheet composed of two-unit
membranes)
Rough ER;
lamellar
____ - ER tends to be ___; major site of lipid synthesis and membrane assembly
Smooth ER;
tubular
Proteins and Polysaccharides for Secretion Are Processed in the ___
Golgi Apparatus