Chapter 1: Cell Biology. Flashcards
Increases membrane fluidity
Cholesterol
Determinants of cellular charge
Cells are more negative on the inside compared to the outside based on Na/K ATPase (3Na out / 2K in)
Used for co-transport of glucose proteins and other molecules
Sodium gradient
[Na] ECF
140
[K] ECF
4
[Ca] ECF
5
[Mg] ECF
2
[Cl] ECF
103
[HCO3] ECF
24
[SO4] ECF
1
[Protein] ECF
16
[PO4] ECF
2
[Organic anions] ECF
5
Cations in ECF
Sodium, potassium, calcium, magnesium
Anions in ECF
Chloride, bicarb, sulfate, phosphate, proteins, organic anions
[Na] ICF
12
[K] ICF
150
[Ca] ICF
10 x -7
[Mg] ICF
7
[Cl-] ICF
3
[HCO3] ICF
10
[SO4] ICF
-
[HPO4] ICF
116
[Protein] ICF
40
[Organic anions] ICF
-
Adhesion molecules (cell-cell and cell-extracellular matrix, respectively), which anchor cells
Desmosomes / hemidesmosomes
Cell-cell occluding junctions; form an impermeable barrier (e.g., epithelium)
Tight junctions
Allow communication between cells (connexin subunits)
Gap junctions
Intramembrane proteins; transduce signal from receptor to response enzyme
G proteins
Receptor and response enzyme are a single transmembrane protein
Ligand-triggered protein kinase
Glycolipids on cell membrane
ABO blood-type antigens