Chaper 1 and 2 ( The Immune System and Immune Cells)

Question 1

Defensive barriers of the innate immunity ?

Answer 1

1- anatomic and physical ( skin , mucous membrane and normal flora )
2- physiologic ( temperature , pH , antimicrobials and cytokines )
3- complements
4- cellular ( phagocytes and granulocytes )
5- inflammation

Question 2

How the antibodies aid in pathogen destruction ?

Answer 2

Opsonization
Complement activation
Antibody-dependent cellular cytotoxicity

Question 3

What is the factor that induces differentiation of multipotent stem cells into lymphoid stem cell ?

Answer 3

IL-7

Question 4

What is the factors that induce differentiation of multipotent stem cells into myeloid stem cell ?

Answer 4

GM-CSF

IL-3

Question 5

What is the factor that induces differentiation of myeloid stem cells into eosinophil progenitor ?

Answer 5

IL-5

Question 6

Function of neutrophils ?

Answer 6

Phagocytic activity aimed at killing extracellular pathogens

Question 7

Surface markers of B lymphocytes ?

Answer 7

CD 19,20,21

Question 8

Surface markers of helper T cells ?

Answer 8

CD3,4

Question 9

Surface markers of cytotoxic T cells ?

Answer 9

CD3,8

Question 10

Surface markers of natural killer cells ?

Answer 10

CD16,56

Question 11

Location of dendritic cells ?

Answer 11

Resident in epithelial and lymphoid tissues