chap 6 defns Flashcards
malig melanoma
tumor of melanocytes: malig
Exophyphitic lesions
project from surface
Tumor capsule
rim of compressed fibrous tissue comprised of ECM deposited by fibroblasts
-cystadenoma
epithelial neoplasms derived from glands or ducts
-tumors that form large cystic masses.
renal cell carcinoma
renal epithelium: malig
lymphangioma
lymph vessels: benign
carcinoma
Malignant tumors that arise from any of the 3 germ layers
Carcinoma in situ
when there are dysplastic changes in the full thickness of the epithelium but the lesion doesn’t go through the basement membrane.
leukemia
hematopoetic cells: malig
Hamartomas
disorganized but benign masses composed of cells that live in the involved site. - not true neoplasms!
benign fibrous tumor
mesothelium: benign
Scirrhous.
very hard tumor
malig mixed tumor of salivary gland origin
mixed tumor of saliv origin: malig
teratoma
composed of cells from multiple germ layers (from totipotent)
-usu in ovaries/testis and cystic
osteoma
CT and derivatives: benign
teratocarcinoma
immature teratoma: totipotent cells in gonads/embryoinc rests: malig
hemangioma
bvs: benign
osteogenic sarcoma
CT and derivatives: malig
squamous cell carcinoma
stratified squamous epithelia: malig
hepatocellular carcinoma
liver cells epithelium: malig
renal tubular adenoma
renal epithelium: benign
Acanthosis nigricans
A disorder that is characterized by grey-black patches of thickened hyperkeratotic skin with a velvety appearance. (a paraneoplastic synd)
seminoma; embryonal carcinoma
testicular epithelium (germ cells): malig
tumor markers
biochemical assays for tumor assoc enzs, hormones, and other stuff in blood
cystademocarcinoma
epithelial lining of glands/ducts: malig
hypertrophic osteoarthropathy
- periosteal new bone formation, esp at the distal end of long bones and hand/feet joints
- arthritis of the adjacent joints
- clubbing of the digits (can be seen in other stuff)
(a paraneoplastic synd)
-cystadenofirbroma
fiberous and cyst aspects
invasive meningioma
brain covering: malig
Neoplasia
new growth that has rebelled against the masters and is operating on its own.
AKA tumor
wilms tumor
renal anlage: mixed tumor: malig
basal cell carcinoma
basal cell of skin or adnexa: l malig
fibroma
CT and derivatives: benign
meningioma
brain covering: benign
squamous cell papilloma
stratified squamous epithelia: benign
leiomyosarcoma
sm: malig
skip metastasis
lymph nodes can be bypassed due to anastomoses or blockage from inflammation/radiation.
hydratiform mole
placental epithelium: benign
parenchyma
- The part composed of cells
* This is the basis for classification
choriocarcinoma
placental epithelium: malig
chondroma
CT and derivatives: benign
lymphoma
lymphoid tissue: malig
bronchial adenoma
resp passages: benign
-polyp
neoplasms that project above mucosal surface (into gastric/colonic lumen)
-oma
benign (much misuse): from mesenchymal tumors
angiosarcoma
bvs: malig
lipoma
CT and derivatives: benign
fibrosarcoma
CT and derivatives: malig
nevus
tumor of melanocytes: benign
leiomyoma
sm: benign
Desmoplasia
tumors that have lots of collagenous stroma.
chondrosarcoma
CT and derivatives: malig
there are no benign tumors of:
hematopoetic cells, lymphoid tissue, basal cells of skin or adnexa, and testicular epithelium
transitional cell carcinoma
urinary tract transitional epithelium: malig
lymphangiosarcoma
lymph vessels: malig
bronchogenic carcinoma
resp passages: malig
sarcoma
mesenchymal; malig
papillary carcinoma
epithelial lining of glands/ducts: malig
rhabdomyoma
striated m: benign
paraneoplastic synd
=sy/symp that cannot be explained by the anatomic distrib of the tumor or by the elab of hormones indigenous to the tissue from which the tumor arose
(when a (tumor) can elab hormones/hormone like tumors (eg a pheochromocytoma))
pseudomyxoma peritonei
peritoneal surface coated w cancerous glaze
Choristoma
heterotropic rest of cells that is typically totally benign and nothing bad.
borderline
see atypia but don’t know bio propensity – don’t know how aggressive itll get
adenocarcinoma
epithelial lining of glands/ducts: malig
bc/colon canc
mesothelioma
mesothelium: malig
-papilloma
epithelial neoplasms derived from glands or ducts
-tumors that make fingerlike/warty projections from epithelial surfaces
Cancer
generic term for malignant tumors.
liposarcoma
CT and derivatives: malig
pleomorphic adenoma
mixed tumor of saliv origin: benign
transitional cell papilloma
urinary tract transitional epithelium: benign
-papillary cystadenoma
tumors that produce papillary patterns that protrude into cystic spaces.
mixed tumor
composed of cells from 1 germ layer
Reactive stroma
made of CT, bvs, variable numbers of cells of the adaptive and innate immune sys
• This is the reason for their grth and spread
hepatic adenoma
liver cells epithelium: benign
rhabdomyosarcoma
striated m: malig
pre-neoplastic
pre-malig,, may go on to be malig
-adenoma
epithelial neoplasms derived from glands or ducts
dermatoid cyst
=ovarian cystic teratoma
mature teratoma: totipotent cells in gonads/embryoinc rests: benign