Chap. 19 vocab (adrenergic-blocking)

Question 1

acrocynosis

Answer 1

decreased amt of oxygen delivered to the extremities, causing feet / hands to turn blue

Question 2

adrenegric receptors

Answer 2

specific receptor sites located throughout the body for the endogenous sympathetic neurotransmitters norepinephrine and epinephrine

Question 3

agonists

Answer 3

drugs with a specific receptor affinity that mimic the body’s natural chemicals (hormones, neurotransmitters)

Question 4

angina

Answer 4

paroxysmal (sudden) chest pain caused by myocardial ischemia

Question 5

antagonists

Answer 5

drugs that bind to specific receptors and inhibit or block the response of the receptor

Question 6

dysrthmias

Answer 6

irregular heart rhythms; almost always called arrhythmias in clinical practice

Question 7

extravasation

Answer 7

leaking of fluid from a blood vessel into the surrounding tissues, as in the case of an infiltrated intravenous infusion

Question 8

first-dose phenomenon

Answer 8

severe and sudden drop in BP after the admin of the first dose of an alpha-adrenergic blocker

Question 9

intrinsic sympathomimetic activity

Answer 9

paradoxical action of some beta-blocking drugs (acebutolol) that mimics the action of the SNS

Question 10

lipophilicity

Answer 10

chemical attraction of a substance to lipid or fat molecules

Question 11

orthostatic hypotension

Answer 11

sudden drop in BP when standing up

Question 12

pheochromocytoma

Answer 12

vascular adrenal gland tumor that is usually benign but secretes epinephrine and nor epinephrine and thus often causes CNS stimulation and substantial BP elevation

Question 13

Raynaud’s disease

Answer 13

narrowing of small arteries that limits the amt of blood circulation to the extremities, causing numbness of the nose, fingers, toes and ears in response to cold temps or stress

Question 14

sympatholytics

Answer 14

drugs that inhibit the postganglionic functioning of the SNS