CHAP 13 Flashcards
What are acellular disease-causing agents that lack cell structure and cannot metabolize, grow, self- reproduce, or respond to their environment.
Viruses, viroids, and prions
a tiny infectious agent with nucleic acid
Virus
nucleic acid surrounded by proteinaceous capsomeres that form a coat are called?
Capsid
It exists in an extracellular state and an intracellular state
Virus
a complete viral particle, including a nucleic acid and a capsid, outside a cell.
Virion
They include either DNA or RNA. Viral genomes may be dsDNA, ssDNA, dsRNA, or ssRNA They may exist as linear or circular and singular or multiple molecules of nucleic acid, depending on the type.
Genomes of virus
are specific for their hosts’ cells because viral attachment molecules are complementary in shape to specific receptor mole- cules on the host’s cells.
Virus
All types of organisms can be infected by ?
Viruses
a virus that infects a bacterial cell.
bacteriophage
can have a membranous envelope or be naked—that is, have no envelope.
Virions
are classified based on type of nucleic acid, presence of an
envelope, shape, and size.
Viruses
Who has recognized viral family and genus names. With the exception of three orders, higher taxa are not established.
International Committee on Taxonomy of Viruses (ICTV)
Viruses depend on random contact with a specific host cell type for replication. Typically, a virus in a cell proceeds with what cycle?
lytic replication cycle
What are the stages of lytic replication cycle?
attachment, entry, synthesis, assembly, and release.
With animal viruses, the entire virion often enters the cell, where the capsid is then removed in a process called
Uncoating
Within the host cell, the viral nucleic acid directs synthesis of more viruses using what?
metabolic enzymes and ribosomes of the host cell.
Assembly of synthesized virions occurs in?
Host cell
Virions are released from the host cell either by?
lysis of the host cell (seen with phages and animal viruses) or by the extrusion of enveloped virions through the host’s cytoplasmic membrane (budding)
a process seen only with certain animal viruses.
Budding
Temperate phages (lysogenic phages) enter a bacterial cell
and remain inactive in a process called
lysogeny or lysogenic replication cycle
inactive phages are called what and are inserted into the chromosome of the cell and passed to its daughter cells.
prophages
results when phages carry genes that alter the phenotype of a bacterium
Lysogenic conversion
At some point in the generations that follow, a prophage may be excised from the chromosome in a process known as
induction
During induction,
the prophage again becomes a
lytic virus
dsDNA viruses use their DNA like cellular DNA in transcription and replication except?
hepatitis B virus
These viruses have positive-sense single-stranded RNA, which can be directly translated by ribosomes to synthesize protein.
ssRNA
From the positive-sense single-stranded RNA (∙ssRNA) what is transcribed to serve as a template for more + ssRNA.
complementary negative-sense single-stranded RNA ( - ssRNA)
carry reverse transcriptase, which transcribes DNA from RNA.
Retroviruses (HIV, +ssRNA)