CHAP 13 Flashcards

1
Q

What are acellular disease-causing agents that lack cell structure and cannot metabolize, grow, self- reproduce, or respond to their environment.

A

Viruses, viroids, and prions

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2
Q

a tiny infectious agent with nucleic acid

A

Virus

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3
Q

nucleic acid surrounded by proteinaceous capsomeres that form a coat are called?

A

Capsid

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4
Q

It exists in an extracellular state and an intracellular state

A

Virus

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5
Q

a complete viral particle, including a nucleic acid and a capsid, outside a cell.

A

Virion

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6
Q

They include either DNA or RNA. Viral genomes may be dsDNA, ssDNA, dsRNA, or ssRNA They may exist as linear or circular and singular or multiple molecules of nucleic acid, depending on the type.

A

Genomes of virus

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7
Q

are specific for their hosts’ cells because viral attachment molecules are complementary in shape to specific receptor mole- cules on the host’s cells.

A

Virus

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8
Q

All types of organisms can be infected by ?

A

Viruses

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9
Q

a virus that infects a bacterial cell.

A

bacteriophage

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10
Q

can have a membranous envelope or be naked—that is, have no envelope.

A

Virions

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11
Q

are classified based on type of nucleic acid, presence of an
envelope, shape, and size.

A

Viruses

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12
Q

Who has recognized viral family and genus names. With the exception of three orders, higher taxa are not established.

A

International Committee on Taxonomy of Viruses (ICTV)

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13
Q

Viruses depend on random contact with a specific host cell type for replication. Typically, a virus in a cell proceeds with what cycle?

A

lytic replication cycle

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14
Q

What are the stages of lytic replication cycle?

A

attachment, entry, synthesis, assembly, and release.

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15
Q

With animal viruses, the entire virion often enters the cell, where the capsid is then removed in a process called

A

Uncoating

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16
Q

Within the host cell, the viral nucleic acid directs synthesis of more viruses using what?

A

metabolic enzymes and ribosomes of the host cell.

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17
Q

Assembly of synthesized virions occurs in?

A

Host cell

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18
Q

Virions are released from the host cell either by?

A

lysis of the host cell (seen with phages and animal viruses) or by the extrusion of enveloped virions through the host’s cytoplasmic membrane (budding)

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19
Q

a process seen only with certain animal viruses.

A

Budding

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20
Q

Temperate phages (lysogenic phages) enter a bacterial cell
and remain inactive in a process called

A

lysogeny or lysogenic replication cycle

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21
Q

inactive phages are called what and are inserted into the chromosome of the cell and passed to its daughter cells.

A

prophages

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22
Q

results when phages carry genes that alter the phenotype of a bacterium

A

Lysogenic conversion

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23
Q

At some point in the generations that follow, a prophage may be excised from the chromosome in a process known as

A

induction

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24
Q

During induction,
the prophage again becomes a

A

lytic virus

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25
Q

dsDNA viruses use their DNA like cellular DNA in transcription and replication except?

A

hepatitis B virus

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26
Q

These viruses have positive-sense single-stranded RNA, which can be directly translated by ribosomes to synthesize protein.

A

ssRNA

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27
Q

From the positive-sense single-stranded RNA (∙ssRNA) what is transcribed to serve as a template for more + ssRNA.

A

complementary negative-sense single-stranded RNA ( - ssRNA)

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28
Q

carry reverse transcriptase, which transcribes DNA from RNA.

A

Retroviruses (HIV, +ssRNA)

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29
Q

carry an RNA-dependent RNA transcriptase for transcribing mRNA from the - ssRNA genome, and the mRNA is translated to protein.

A

Negative-sense single-stranded RNA (-ssRNA)

30
Q

these viruses, the positive strand of RNA functions as mRNA, and each strand functions as a template for an RNA complement.

A

dsRNA

31
Q

a process similar to lysogeny, an animal virus remains inactive in a cell, possibly for years, as part of a chro- mosome or in the cytosol.

A

Latency

32
Q

also known as a provirus.

A

Latent virus

33
Q

is uncontrolled cellular reproduction in a multicel- lular animal.

A

Neoplasia

34
Q

A mass of neoplastic cells

A

Tumor

35
Q

A mass of neoplastic cells relatively harmless

A

Benign tumor

36
Q

A mass of neoplastic cells invasive

A

malignant tumor

37
Q

Malignant tumors are also called?

A

Cancer

38
Q

describes the spreading of malignant tumors.

A

Metastasis

39
Q

Environmental factors or oncogenic viruses may cause?

A

Neoplasia

40
Q

In the laboratory, viruses must be cultured inside mature organ- isms, in embryonated chicken eggs, or in cell cultures because?

A

viruses cannot metabolize or replicate alone.

41
Q

When a mixture of bacteria and phages is grown on an agar plate, bacteria infected with phages lyse, producing clear areas called?

A

Plaques on the bacterial lawn.

42
Q

A technique used to estimate phage numbers.

A

Plaque assay

43
Q

Viruses can be grown in two types of ?

A

Cell cultures

44
Q

What culture last about 100 generations,

A

diploid cell cultures

45
Q

What cell culture is derived from cancer cells, last longer.

A

continuous cell cultures

46
Q

Outside cells, viruses do not appear to be alive, but within cells,
they exhibit lifelike qualities, such as the ability to replicate.

True or False

A

True

47
Q

are small circular pieces of RNA with no capsid that infect and cause disease in plants

A

Viroids

48
Q

pathogenic RNA mole- cules have been found in

A

Fungi

49
Q

are infectious protein particles that lack nucleic acids

A

Prions

50
Q

replicate by inducing similar, normal proteins to misfold into new prions—a process called

A

Templating

51
Q

Diseases caused by these are spongiform encephalopathies, which involve fatal neurological degeneration.

A

Prions

52
Q

Which of the following is not an acellular agent?

a. viroid
c. rickettsia
b. virus
d. prion

A

c. rickettsia

53
Q

Which of the following statements is true?
a. Viruses move toward their host cells.
b. Viruses are capable of metabolism.
c. Viruses lack a cytoplasmic membrane.
d. Viruses grow in response to their environmental conditions.

A

c. Viruses lack a cytoplasmic membrane.

54
Q

A virus that is specific for a bacterial host is called a

a. phage
c. virion
b. prion
d. viroid

A

a. phage

55
Q

A naked virus __________________.
a. has no membranous envelope
b. has injected its DNA or RNA into a host cell c. is devoid of capsomeres
d. is one that is unattached to a host cell

A

a. has no membranous envelope

56
Q

Which of the following statements is false?

a. Viruses may have circular DNA.
b. dsRNA is found in bacteria more often than in viruses.
c. Viral DNA may be linear.
d. Typically, viruses have DNA or RNA but not both.

A

b. dsRNA is found in bacteria more often than in viruses.

57
Q

When a eukaryotic cell is infected with an enveloped virus and sheds viruses slowly over time, this infection __________________.
a. is called a lytic infection
b. is a prophage cycle
c. is called a persistent infection
d. is caused by a quiescent virus

A

c. is called a persistent infection

58
Q

Another name for a complete virus is __________________.
a. virion
b. viroid
c. prion
d. capsid

A

a. virion

59
Q

Which of the following viruses can be latent?
a. HIV
b. chicken pox virus
c. herpesviruses
d. all of the above

A

d. all of the above

60
Q

Which of the following is not a criterion for specific family classi- fication of viruses?
a. the type of nucleic acid
b. envelope structure
c. capsid type present
d. lipid composition

A

d. lipid composition

61
Q
  1. A clear zone of phage infection in a bacterial lawn is __________________.
    a. a prophage
    b. a plaque
    c. naked
    d. a zone of inhibition
A

b. a plaque

62
Q

harmless neoplastic cells

A

benign tumor

63
Q

invasive neoplastic cells

A

cancer

64
Q

removal of capsomeres from a virion

A

uncoating

65
Q

inactive virus within bacterial cell.

A

prophage

66
Q

complete viral particle

A

virion

67
Q

a membrane on the outside of a virus.

A

envelope

68
Q

protein coat of virus

A

Capsid

69
Q

transcribes DNA from RNA

A

Retrovirus

70
Q

a virus that infects a bacterium.

A

Bacteriophage

71
Q

dormant virus in a eukaryotic cell.

A

Provirus