Ch9: Cancers Common In Midlife Women

Question 1

Breast cancer treatment for women with:
estrogen and/or progesterone receptor positive
human epidermal growth factor receptor (HER2) negative
3 or fewer positive lymph nodes

Answer 1

Chemotherapy base on tumor’s onco-type recurrence score

Question 2

Breast cancer treatment for women with:
triple negative disease (ER-, PR-, HER2- receptor)
positive lymph nodes

Answer 2

Anthracycline and taxane chemotherapy unless contraindicated

Question 3

Breast cancer treatment for women with:
HER2 positive
2cm or smaller
negative lymph nodes

Answer 3

Weekly taxol for 12 weeks
Combined with trastuzumab (Herceptin) for one year
4 year overall survival of 95%

Question 4

Breast cancer treatment for women with:
HER2 positive
larger >2cm
nodal metasases

Answer 4

Chemotherapy with 1 year of trastuzumab (Herceptin, HER2 antagonist)
And possible pertuzumab

Question 5

Breast cancer treatment for women with:

larger tumors who desire breast conservation

Answer 5

Initial treatment with chemotherapy or endocrine therapy may downstage the tumor

Question 6

Breast cancer treatment for women with:

locally advanced disease

Answer 6

Initial treatment with chemotherapy or endocrine therapy may downstage the tumor