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HEMOTOLOGY > CH.6 > Flashcards

CH.6 Flashcards

1
Q

how many ATPs does glycolysis make

A

4

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2
Q

what is the net ATP for RBCs during glycolysis

A

2

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3
Q

what is the most important energy source in glycolysis

A

glucose

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4
Q

what is the purpose of glycolsis

A

break down glucose

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5
Q

what do free radical do

A

take away e-

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6
Q

what reduces glutathione

A

NADPH

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7
Q

what converts H2O2 to 2 H20

A

glutathione

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8
Q

funtion of BPGM

A

changes the position of the phosphate

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9
Q

if glycolisis takes the BPGM pathway what happens to ATP production

A

skips making 1 ATP

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10
Q

what does 2,3-bisphosphoglycerate bind to

A

hemoglobin

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11
Q

if O2 can not bind to hemoglobin because of 2,3-bisphosphoglycerate what happens

A

O2 is released in the tissues

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12
Q

what gets detoxified in the hexose monophosphate pathway

A

peroxide

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13
Q

what changes glucose-6-phosphate to pentose phosphate in the hexose monophasphate pathway

A

glucose-6-phosphate dehydrogenase (G6PD)

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14
Q

what is the most common enzyme deficiency

A

G6PD

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15
Q

what do degmacytes indicate

A

heinz bodies

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16
Q

what do macrophages do to RBCs with ozidized hemoglobin when they pass through the spleen

A

they destroy part of it

17
Q

how many iron molecules are in a RBC

A

4

18
Q

is ferrous hemoglobin reduced or oxidized

A

reduced

19
Q

is ferric hemoglobin reduced or oxidized

A

oxidized

20
Q

can O2 bind to methemoglobin

A

no

21
Q

what condition does glutamate replace valine in position 67 on the beta chain

A

hemoglobin M

22
Q

does methemoglobin increase or decrease in Hemoglobin condition

A

increase

23
Q

what medicine do people take with hemoglobin M condition

A

metholine blue pill

24
Q

T or F: methylene blue is a reducing agent

A

T

25
Q

what changes when a RBC becomes a target cell

A

change in the phospholipid bilayer

26
Q

what is the reason why when 2 RBC touch they don’t merge

A

glycolipids

27
Q

what kind of proteins connect horizontal proteins to mmb

A

vertical

28
Q

what happens to a RBC if it’s shape is changed

A

it will die

29
Q

what happens to a RBC deformability as they age

A

it decreases

30
Q

if there is a problem with a RBC horizontal proteins what kind of cell will it be

A

elipocyte

31
Q

what kind of environment would you find spherocytes

A

hypotonic

32
Q

what kind of environment would you find enchinocytes

A

hypertonic

33
Q

what kind of environment would you find normal RBC

A

isotonic

HEMOTOLOGY (6 decks)

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