CH.6 Flashcards
how many ATPs does glycolysis make
4
what is the net ATP for RBCs during glycolysis
2
what is the most important energy source in glycolysis
glucose
what is the purpose of glycolsis
break down glucose
what do free radical do
take away e-
what reduces glutathione
NADPH
what converts H2O2 to 2 H20
glutathione
funtion of BPGM
changes the position of the phosphate
if glycolisis takes the BPGM pathway what happens to ATP production
skips making 1 ATP
what does 2,3-bisphosphoglycerate bind to
hemoglobin
if O2 can not bind to hemoglobin because of 2,3-bisphosphoglycerate what happens
O2 is released in the tissues
what gets detoxified in the hexose monophosphate pathway
peroxide
what changes glucose-6-phosphate to pentose phosphate in the hexose monophasphate pathway
glucose-6-phosphate dehydrogenase (G6PD)
what is the most common enzyme deficiency
G6PD
what do degmacytes indicate
heinz bodies
what do macrophages do to RBCs with ozidized hemoglobin when they pass through the spleen
they destroy part of it
how many iron molecules are in a RBC
4
is ferrous hemoglobin reduced or oxidized
reduced
is ferric hemoglobin reduced or oxidized
oxidized
can O2 bind to methemoglobin
no
what condition does glutamate replace valine in position 67 on the beta chain
hemoglobin M
does methemoglobin increase or decrease in Hemoglobin condition
increase
what medicine do people take with hemoglobin M condition
metholine blue pill
T or F: methylene blue is a reducing agent
T
what changes when a RBC becomes a target cell
change in the phospholipid bilayer
what is the reason why when 2 RBC touch they don’t merge
glycolipids
what kind of proteins connect horizontal proteins to mmb
vertical
what happens to a RBC if it’s shape is changed
it will die
what happens to a RBC deformability as they age
it decreases
if there is a problem with a RBC horizontal proteins what kind of cell will it be
elipocyte
what kind of environment would you find spherocytes
hypotonic
what kind of environment would you find enchinocytes
hypertonic
what kind of environment would you find normal RBC
isotonic
