Ch24 FA synthesis

Question 1

What are the 4 dif. b/w FA synthesis & breakdown?

Answer 1

1/ NADPH vs NADH
2/ -SH onto acyl carrier protein
3/ Enzyme syn: 1 polypep - fatty acid synthase
4/ S: cytosol, B: mito

Question 2

Strategy for synthesize FA?

Answer 2

1/ add 2C from AcCoA
2/ activate AcCoA by adding CO2 & form malonyl-CoA
(cost ATP)

3/ Repeat elongation until palmitate (16C)
4/ Other enzyme add C=C or grow chain longer