ch.14 slide 110-123 Flashcards
what is a polyp?
mass that protrudes into lumen- epithelial or mucosal proliferation
types of polyps?
pedunculated or sessile
characteristics of polyps?
- inflammatory
- hamartomas
- hyperplastic MC in elderly
4 adenomatous
are adenoma hereditary? how common are they?
yes. 4x risk for familial
50% of all U.S. adults >50 yr old
familial adenomatous polyposis is??
a rare autosomal dom., aggressive & numerous adenomas
- genetic mutation APC gene (chrom 5)
- 100% of ca, MC by age 30
Tx of familial adenomatous polyposis?
prophylactic colectomy
types of colon tumors?
adenocarcinomas
carcinoid tumors
MC colon tumors? what % is lethal?
Carcinoma of epithelial tissue
40% is lethal
5% of U.S. pop. develops colorectal CA
what is the MC malignancy of GI tract?
colorectal adenocarcinoma
risks for colorectal adenocarcinoma?
Male; 50-70 yr olds; IBD; Developed nations
highly processed foods Inc by 30x
food risks for colorectal adenocarcinoma?
low fiber
refined carbs
high fat
dec. antioxidants
where does colorectal adenocarcinomas mets to?
regional lymphatic’s & hematopoietic
MC liver, lymph nodes, lungs, bone marrow
neoplasms of SI occur MC where? how often?
Duodenum
very rare: 3-6% of GI tumors
1% of GI malignancies
acute appendicitis is? how common?
MC acute abdominal condition
consists of RLQ tenderness
anorexia, nausea, vomiting, pyrexia
- 7% of U.S. pop.
who is at risk for appendicitis?
males 1.5x, 20-40 yrs. old