Ch12 Cns Depressants Flashcards
Benzodiazepines (lam-Pam)
Can either be sedative-hypnotic or anxiolytic (relieves anxiety)
-depresses cns activity affects hypothalamic,that iv limbic
-indications-sedation anxiety agitation depression epilepsy treatment of withdraws and seizures
-dosent suppress rem
Benzo antidote
Flumazenil
Kava
Natural herb to promote sleep
-May cause yellow skin discoloration and visual disturbance
- contraindications patients with liver disease alcoholism
Valerian
Herbal product to relieve anxieties and sleep disorders
May interact with maois, warfarin,alcohol,phenytoin
Contradicted in cardiac and liver disease
Diazepam
Anxiolytic and Sedative
It can treat anxiety, muscle spasms, and seizures.
First clinical available benzo drug
Midazolam
Most commonly used for moderate sedation
-causes amnesia
Normally injected adults and oral form form for children
Pentobarbital
Short acting barbituate It can treat tension, anxiety, nervousness, and trouble falling asleep (insomnia). It can help patients relax before surgery or medical procedures. In addition, it can treat epilepsy and other seizures.
Oral injections rectal dose
Phenobarbital
Long lasting drug
No longer recommend for hypnotic drug
Treatment for epilepsy
Over the counter hypnotics
Doxylamine and diphenhydramine and acetaminophen
Muscle relaxers
Baclofen- oral or injections
It can treat muscle spasms.
-implant baclofen pump device
Cyclobenzaprine
Oral extendable release oral form
Most common muscle relaxers
Centrally acting
Hypnotic should be given when before bed for max effectiveness
30-60 mins before bed
Benzo cause
REM rebound tired the next day