ch 33 adrenal drugs

Question 1

Over secretion of adrenocortical hormones leads to?

Answer 1

Cushing’s syndrome
-purple striae
-moon face
-na fluid retention
-hyperglycemia

Question 2

Undersecretion

Answer 2

Addison’s disease
-weight loss
-postural hypotension
-hypoglcemia
-bronze skin tone

Question 3

Glucocorticoids

Answer 3

regulates metabolism of carbs (can increase blood glucose)
- suppresses immune responses/ supports adaptation during times of stress/ Topical/ inhalant/ PO/ Parenteral
Contraindicated in infections– immunosuppressive agent

Question 4

Betamethasone

Answer 4

fetal maturation of lungs

Question 5

Methylprednisolone

Answer 5

most common injection
-cannot be used in children less than 28 days b/c benzyl alcohol preservative

Question 6

Prednisone

Answer 6

most common PO, anti inflammatory and immunosuppressive purposes, exacerbation in respiratory conditions like COPD and asthma

Question 7

Mineralocorticoids

Answer 7

regulate mineral salts (fluids and electrolytes)

Question 8

Aldosterone

Answer 8

maintains normal levels of sodium in the blood/ Na+ reabsorption from the urine back into the blood

Question 9

Fludrocortisone

Answer 9

used for addison’s disease and adrenocortical insufficiency, increases retention of Na+ and water and loss of potassium/ contraindicated in systemic fungal infections/ adverse effects-edema, hypertension, weight gain (2lbs or more a day/ 5lbs or more a week), hyperglycemia, hypokalemia, compression bone fractures, increase ulcer risk