Ch. 61 Flashcards
__ is the single most important determine for fetal viability
Adequacy of pulmonary development
__ is the major reason fetuses younger than 24 weeks are generally considered nonviable
Pulmonary immaturity
Breathing movements that occur before birth results in _
Aspiration of fluid into the lungs
The lungs at birth are about half filled with
Fluid from the amniotic cavity
The fluid in the lungs at birth clears via 3 routes:
Nose and mouth
Into pulmonary capillaries
Into lymphatic and pulmonary vessels
Normally the thoracic cavity is
Symmetric and bell shaped
The lungs serve as __ for the heart, and lie __ to the diaphragm
Lateral borders
Superior
The diaphragm can be seen as __ between the fetal liver and lungs
A smooth hypoechoic muscular curvilinear margin
Normally the fetal thorax is slightly __ than the abdominal cavity
Smaller
The ratio [TC:AC] __ throughout pregnancy
Remains constant
Extreme variations in thoracic size should signal
Further investigation for other anomalies
___ can result in pulmonary hypoplasia, which may cause __
Oligohydramnios
Overall reduction in the thoracic size
Thoracic circumference measurements are made in the __ plane at the level of __
Transverse
4 chamber heart
A fetus that has significantly narrower chest diameter may have
Asphyxiating thoracic dystrophy
Sever syndromes are associated with asphyxiating thoracic dystrophy including
Dwarfism
The majority of the heart is positioned in the
Midline and left chest
The apex of the heart should be directed
Toward the spleen (left)
It is important to document sonographically the position of the
the heart
Detection for abnormal position of the heart may indicate the presence of
Chest mass
Pleural effusion
Cardiac malformation
Fetal lungs appear
Homogeneous with moderate echogenicity
Echogenicity of the fetal lungs __ as pregnancy progresses
Increases
Fetal breathing becomes ___ in the 2nd & 3rd trimesters
More prominent
A mature fetus spends almost __ of its time “breathing”
1/3
Color doppler may be used to detect __, however it is not a well-recognized practice
fetal breathing through the nostrils
When evaluating the fetus for a lung mass the following should be assessed
Position of the fetal heart
Orientation of the cardiac axis (normal is 45 degree angle pointing left)
Measurement of the thoracic circmference
Deviation from the normal cardiac axis may suggest the presence of
an intrathoracic mass
Thoracic circumference measurements estimate ___& may predict ___
the size of the thoracic cavity
secondary pulmonary hypoplasia
When the heart position & axis vary from the normal position:
look closely for any abnormalities that may be causing the displacement such as pleural effusion or diaphragmatic hernia
Lungs may not grow or develop properly with
oligohydramnios
A mass within the throacic cavity may have ___ on lung development. The heart may be displaced & the lungs may be __. These effects may lead to __
detrimental effects
compressed and destroyed
pulmonary hypoplasia
Pulmonary hypoplasia is caused by __ and results in __
a decrese in the number of lung cells, airways, and alveoli
decrease in organ size and weight
Reduction in lung volume results in __
small inadequately developed lungs
Pulmonary hypoplasia most commonly ocurs from __ or secondary to __
prolonged oligohydramnios
small thoracic cavity as a result of structural or chromosomal abnormality
Kidney abnormalities may result in __
lethal pulmonary hypoplasia
Kindey abnormalities that may result in lethal pulmonary hypoplasia
▪Bilateral renal agenesis ▪Bilateral multicystic kidney disease ▪Severe renal obstruction ▪Unilateral renal agenesis with contralateral multicystic kidney development ▪Severe obstruction ▪Infantile polycystic kidney disease
Pulmonary hypoplasia may occur in fetuses with
severe IUGR & early rupture of membranes
Masses within the thoracic cavity may lead to
Pulmonary hypoplasia
Abnormalities that can cause pulmonary hypoplasia are
▪Cardiac defects
▪Some skeletal dysplasias
▪CNS disorders
▪Chromosomal Trisomies
A small percentage of infants have pulmonary hypoplasia without
any fetal or uterine problems
_ pulmonary agenesis or hypoplasia is rare, often associated with __
Unilateral
other fetal abnormalities
An absent lung should be considered a differential diagnosis of every fetus with
mediastinal shift and apparent chest mass
Prognosis of pulmonary hypoplasia
grave
80% die after birth
Severity of pulmonary hypoplasia depends on
▪when pulmonary hypoplasia occured during pregnancy ▪severity ▪duration Other contributing factors: ▪Pulmonary fluid dynamics ▪Fetal breathing movements ▪Hormonal influences
Various methods are used to determine the presence of pulmonary hypoplasia
▪thoracic measurements ▪Various lung measurements ▪Estimation of lung volume ▪Doppler studies of pulmonary arteries ▪Assessment of fetal breathing activity
A thoracic circumference below the _____percentile suggests the possibility of pulmonary hypoplasia
5th
Cystic Lung Masses
Echo free masses that replace normal lung parenchyma
Cystic lung masses vary in __
size, ranging from small isolated lesions to large cystic masses
Cystic lung masses may cause
notable shifts of intrathoracic structures
Simple cysts may be
surgically removed after delivery
Most common lung cyst detected prenatally
Bronchogenic cysts
Bronchogenic cysts occur as a result of
abnormal budding of the foregut
Brochogenic cysts lack
any communication with the trachea or bronchial tree
Isolated
Bronchogenic cysts typically occur within the
mediastinum or lung
Bronchogenic cysts infrequently found
inferior to the diagram
Sono appearance of bronchogenic cysts
- Appear as small circumscribed masses
- No evidence of mediastinal shift or heart failure
- Amniotic fluid within normal range
Accumulation of fluid within the pleural cavity
Pleural effusion
Pleural effusion may appear as
an isolated lesion or secondary to multiple fetal anomalies
Most common reason for pleural effusion
Chylothorax
Chylothorax
- Occurring as a right sided unilateral collection of fluid secondary to malformed thoracic duct
- Hydramnios often accompanies chylothorax resulting from esophageal compression
Pleural effusion can be
unilateral or bilateral
Pleural eeffusion may result from
immune [Rh isoimmunization] or nonimmune causes or from congestive heart failure
Effusions may also occur in fetuses with:
Chromosomal abnormalities (21) & cardiac mass
Other reasons for pleural effusions
▪Lymphangietctasia ▪Cystic adenomatoid malformations ▪Bronchopulmonary sequestration ▪Diaphragmatic hernia ▪Hamartoma ▪Atresia of pulmonary vein ▪Unknown causes
Sono findings of pleural effusion
▪Echo-free peripheral masses on one or both sides of the fetal heart
▪Conform to the thoracic cavity & often compress the lung tissue
▪Lung appears to float in the fluid
Pleural effusions are rarely seen before _, except when __
15 weeks gestation associated with Down or Turner syndrome
With pleural effusion, Compression of lung parenchyma may cause __, often represents __
pulmonary hypoplasia
life threatening consequences for neonate
The presence of pleural effusion may cause:
▪a shift in medistinal structure
▪Compression of the heart
▪Inversion of the diaphragm
Mortality rate of pleural effusion
approx. 50%
Prognosis of pleural effusion
poorer with associated hydrops
When pleural effusion is large
▪Lung development is impaired
▪Pulmonary hypoplasia may result
Solid lung masses appear as
echo-dense (hyperechoic) masses in the lung tissue
Pulmonary sequestration and certain types of cystic adenomatoid malformations (CCAMs) appear as
solid masses
Pulmonary sequestration
supernumerary lobe of the lung (extra lung tissue) separated from the normal tracheobronchial tree
Intralobar pulmonary sequestration
There is extra lung tissue present within the pleural lung sac
Extralobar pulmonary sequestration
Lung tissue is connected to the inferior border of the lung within its own pleural sac
Pulmonary sequestration most likely develops from either
A separate outpuching of foregut
Separation of a segment of developing lung from the tracheobronchial tree
with pulmonary sequestration the extra lung tissue is
non-functional & receives blood supply from systemic circulation
Sono findings of pulmonary sequestration
▪Echogenic solid mass resembling lung tissue, usually in the lower lobe of the lung
▪Usually on the left side
▪Rarely occurs below the diaphragm
Pulmonary sequestration is associated with
▪Hydrops ▪Polyhydramnios ▪Diaphragmatic hernia ▪Gastrointestinal anomalies ▪Lung anomalies [pulmonary hypoplasia]
Prognosis of pulmonary sequestration
▪Intralobar sequestration has a highly favorable prognosis
▪Extralobar sequestration carries a poor prognosis
Becuase of associated anomalies and hydrops
Congenital Cystic Adenomatoid Malformation([CCAM)
multicystic mass within the lung Consists of primitive lung tissue & abnormal bronchial and bronchial-like structures
CCAM is one of the
bronchopulmonary foregut malformations
CCAM lesions may involv
▪One or more lobes of lung
▪Entire lung
▪Be bilateral
CCAM malformations may
communicate with the bronchial tree
With CCAM, cysts within the mass may be
large or small
Texture of CCAMs
Varies:
solid
cystic
mixed
With CCAM, most lesions are
unilateral and do not favor either lung
3 forms of CCAM
Type 1- macrocystic
Type 2- macrocystic w/ microcystic components
Type 3- Microcystic
CCAM type 1
Macrocystic
•One or more large cyst replaces normal lung tissue
•Single or multiple cysts measuring 2cm up to 10 cm
CCAM type 2:
Anomalies may include:
Macrocystic with microcystic components
•Lesions consist of multiple small cysts <1cm
•Associated with fetal &/or chromosomal abnormalities in 25% of cases:
Renal agenesis
Pulmonary anomalies
Diaphragmatic hernia
CCAM Type 3
Micocystic •Bulky, large, noncystic lesions •Appear as echo-dense [hyperechoic] masses of the entire lung lobe •When mediastinal structures shift oLung compression may occur oHydrops may develop •Hydramnios may be seen secondary to esophageal compression oPreventing normal fetal swallowing
When a cystic or solid lung mass is identified the sonographer should attempt to
▪Determine the number & size(s) of the cystic structure(s)
▪Check for presence or absence of a mediastinal shift
▪Identify & assess the size of the lungs
▪Look for fetal hydrops
▪Exclude cardiac masses
▪Search for other fetal anomalies
Progsis of CCAM
the type of lesion
type 1- favorable outcome
type 2 &3- poor prognosis
Smaller cysts= _ prognosis
poorer
Congenital Bronchial Atresia
Rare
Results from focal obliteration of a segment of the bronchial lumen
Most common in left upper lobe
Appears as an echogenic pulmonary mass lesion
Normally, the diaphragm should appear as a
curvilinear hypoechoic structure coursing anteriorly to posteriorly
The fetal stomach & liver should be identified _to the diaphragm
caudal/ inferior
The fetal lungs and heart should be identified _to the diaphragm
Cephalad/ superior
Failure to see normal relationships to the diaphragm indicates
diaphragmatic defects
Congenital Diaphragmatic Hernia [CDH]
Herniation of the abdominal viscera into the chest
CDH results from
congenital defect in the fetal diaphragm
Most posterior aspect of the diaphragm:
forms last
most commonly defective
Hernia permits abdominal organs to
enter the chest
Herniation through Foramen of Bochdalek
Most common type of diaphragmatic defect
▪Occurs posteriorly & laterally in the diaphragm
•This abnormality positions the heart & mediastinal structures to the right side of the chest
•Look for stomach, portions of small & large intestines, left lobe of liver & spleen in thoracic cavity
•bowel loops may be seen within the thoracic cavity
How would you distinguish loops of bowel vs a mass
bowel has peristalsis
Herniation through foramen bochdalek accounts for more than
90% of diaphragmatic defects
Herniation through foramen bochdalek usually occurs on the
left side of the diaphragm
Diaphragmatic herniation through the foramen of Morgagni
Anteriorly & medially
May communicate with the pericardial sac
The heart & stomach may be normally positioned
With Diaphragmatic herniation through the foramen of Morgagni, herniation is on the _, allowing
right side of the diaphragm
the right sided abdominal viscera to enter the chest (liver, GB, intestines)
Herniated abdominal organs cause
lung compression
With Diaphragmatic herniation through the foramen of Morgagni Size of defects can vary. Range from
small to large to complete absence of both diaphragms
Smaller defects are more difficult to diagnose in utero
Hydrops is usually not present with _ CDH
left sided unless associated fetal malformations are present
with hernias, Pulmonary arteries become _
Results in_
After birth, _
hypertrophied & thickened
Results in pulmonary HTN
After birth, leads to persistent fetal circulation
B/L hernias are
very unusual
more difficult to detect
Cardio-mediastinal shift may not be present
Sonographically:
Left-sided CDH
- Intrathoracic stomach
- Displaced cardiac apex
- Cardio-mediastinal shift [critical in making diagnosis]
- Intrathoracic liver
- Small right lung
- Small left ventricle of heart
- Evaluate for chromosomal abnormalities
Sonographically:
Right-sided CDH
•Liver appears in the chest •Possibly collapsed bowel •Heart deviated to the left •Abnormal stomach alignment •Respirations may be severely compromised •May result in death of the newborn
CDH prognosis
Poor prognosis if: •Detected before birth •Stomach is found in the ches •Left side of heart is undeveloped •Congenital heart disease is present
▪
With CDH, Primary cause of death is
pulmonary hypoplasia
With CDH, if __Survival rate is low
diagnosis is made before 25 weeks & polyhydramnios is present
Anomalies associated with CDH
▪Cardiac malfomations ▪CNS malformations ▪Renal anomalies ▪Vertebral defects ▪Pulmonary hypoplasia ▪Facial clefts ▪Trisomy 18 & 21