Ch. 6 - Casts Flashcards
Casts are formed within the lumens of the _____
Distal convoluted tubules
Collecting ducts
These are the only elements found in the urinary sediment that are unique to the kidney.
Casts
Examination under the microscope of sediments for the identification of casts is performed using what type of objective?
Low-power objective
Major constituents of casts
Tamm-Horsfall protein
A glycoprotein secreted by the RTE cells
Tamm-Horsfall protein
Term used to describe the presence of urinary casts
Cylindruria
What is the most frequently seen cast?
Hyaline casts
Pathologically, hyaline casts are increased during _____
Acute glomerulonephritis
Pyelonephritis
Chronic renal disease
Congestive heart failure
Hyaline casts produces what color when stained with Sternheimer-Malbin stain?
Pink
Presence of ____ casts shows bleeding within the nephron. These are primarily associated with damage to glomerulus (glomerulonephritis).
RBC
RBC casts associated with glomerular damage are usually associated with what diseases?
Proteinuria
Dysmorphic erythrocytes
Presence of ____ casts in the urine signifies infection or inflammation within the nephron
WBC
WBC casts are most frequently associated with what disease?
Pyelonephritis
This type of cast contains bacilli both within and bound to the protein matrix and is seen in pyelonephritis
Bacterial casts
Casts containing RTE cells represents the presence of _____, producing urinary stasis along with disruption of tubular linings.
Advanced tubular destruction