Ch 6 Bipolar and Depressive Disorders Flashcards

1
Q

common symptoms vs clinical depression

A

common for sadness but disorders have longer duration and severity

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2
Q

Major depressive disorder (symptoms, requirements, prevalence, gender differences)

A
  • needs 5 symptoms for at least 2 weeks (persistent low mood/lack of enjoyment)
  • weight/sleep changes
  • low energy
  • agitation (noticeable slower/faster movement)
  • indecisiveness
  • suicidal tendencies
  • insomnia
  • episodic (single vs recurrent)
  • prevalence 5%, women
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3
Q

Persistent depressive disorder (dysthymia) (symptoms and requirements)

A
  • persistent low mood for 2 years + three more symptoms (similar to major depressive)
  • hopeless but not suicidal
  • insomnia
  • up to 2 months symptom-free
  • prevalence 3%
  • less severe but less treatable
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4
Q

double depression

A

persistent depressive disorder with major depressive episodes
- normally when p.d.d. is undiagnosed until m.d. episodes start

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5
Q

disruptive mood dysregulation disorder

A
  • controversial, appeared in DSM5
  • 6-18 intense and inconsistent temper outbursts (3+/week)
  • 12(+) months
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6
Q

depression comorbidity

A

CVD (coronary heart), CNS diseases, cancer, migraines, genetic correlation MDD and anxiety 100%

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7
Q

bipolar disorder 1 manic episode (requirements, symptoms, prevalence)

A
  • 1(+) episodes
  • irritable/elevated mood for 1 week most of the day nearly everyday
    • 3 symptoms: grandiosity, less need for sleep, talkative, goal-directed, racing thoughts, possible depressive episode, irrational gambling
  • 0.8%
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8
Q

bipolar disorder 2 hypomania (requirements, symptoms, prevalence)

A
  • 4 days 1(+) episodes
  • less severe
  • must have depressive episode
  • feeling great -> depressive episodes
  • 0.5%
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9
Q

cyclothymia (definition, duration, prevalence)

A
  • 2 years
  • hypomania subthreshold depression cycles
  • 0.4% - 1%
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10
Q

seasonal affective disorder (prevalence, theories, treatment)

A

Canada: winter months
Prevalence: (general: 2-3%), (MDD: 11%)
- Theories: melatonin, circadian rhythms
- Treatment: phototherapy

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11
Q

psychodynamic explanations

A

abuse/neglect, maladaptive parenting -> vulnerable personality traits (overly dependent, self-critical)

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12
Q

cognitive explanations

A

dysfunctional thinking, negative schemas

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13
Q

interpersonal model explanations

A
  • deficits in social skills (withdrawal -> forgetting)
  • negative feedback seeking
  • excessive reassurance seeking
  • stress generation hypothesis
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14
Q

Life stress perspective explanation

A

stressful events, loss, abuse

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15
Q

biological explanations

A

adoption/twin studies

  • MMD: 36%
  • bipolar: 75%
  • serotonin regulation: short allele increases stress responsiveness
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16
Q

norepinepherin (depression vs bipolar)

A

d: low levels in severe deprssion, certain symptoms
b: low levels, mania link

17
Q

serotonin (depression vs bipolar)

A

d: fewer receptors, certain symptoms
b: low levels -> mania/mood swings

18
Q

dopamine (depression vs bipolar)

A

d: low levels
b: low levels, high levels trigger mania/psychosis

19
Q

3 CBT intervention techniques for depression

A
  1. active scheduling (increase fun activities)
  2. thought records (challenge negative thinking patterns)
  3. behavioural experiments (challenge negative beliefs)
20
Q

CBT vs medication

A

CBT has effective for depression, better LT outcomes

21
Q

behavioural components of CBT

A
  • as effective as full CBT and ST medication

- more effective than LT medication

22
Q

mindfulness cognitive therapy

A
  • more effective vs family doctor and meds
23
Q

interpersonal therapy 4 targets

A

(12-16 sessions focus on one)

  1. role transitions (old and new roles)
  2. communication/problem solving
  3. new relationships, mourning
  4. personality issues that interfere with relationships
24
Q

IPT medication and relapse

A

monthly booster sessions help prevent

25
tricyclics
- antidepressants - block npp reuptake and some serotonin - effective but bad side effects - lethal overdose - rarely used
26
MAOI (monoamine oxidase inhibitors)
- antidepressants - breaks enzymes that breaks neurotransmitters - bad side effects - dietary restrictions ' - rarely used
27
selective serotonin reuptake inhibitors (SSRI)
- first line antidepressants - block serotonin reuptake - mild side effects - safe
28
other antidepressants
- serotonin-norepinephrine reuptake inhibitors - dopamine increase - GABA levels
29
antidepressant effectiveness
- may need to switch to find one suitable - antidepressants > placebos (severe depression) - high relapse - discontinuation syndrome (withdrawal and rebound)
30
lithium
- bipolar medication - effective for mania - monitoring - 40% do not respond or cannot tolerate - high relapse
31
anticonvulsants
- bipolar medication - increase GABA levels, decrease glutamate - used alone or with lithium
32
antipsychotics
- bipolar medication - decrease some neurotransmitter levels - ST for mania, severe deprssion, psychotic symptoms - side effects
33
antidepressants for bipolar
- treats depressive episodes - could trigger manic - + mood stabilizer
34
combining psychotherapy and medication for depression (4 exceptions)
- generally no benefit 1. severe 2. persistent 3. no response 4. adolescents
35
combining psychotherapy and medication for bipolar
- medication is most effective but impairment/relapse 1. family focused therapy 2. interpersonal 3. cognitive
36
biological treatments ( for who, 4 extreme kinds)
- 40% treatment-resistent patients 1. electroconvulsive 2. transcranial magnetic stimulation 3. vagus nerve 4. deep brain
37
ECT
- ~25s seizure - confusion, memory problems - treatment-resistent depression, immediate results - better with higher current and bilateral