Ch 5 Anatomy Flashcards
Three major layers of the skin
Epidermis, Dermis, and Hypodermis
What are the functions of the integumentary system?
- Protection: chemical, physical and mechanical
- Temperature regulation
- Cutaneous sensation
- Metabolic functions: Synthesis of vitamin D
- Blood reservoir: holds 5% of blood volume
- Excretion: some nitrogen wastes lost in sweat
Keratinocytes
Produce keratin which is the fibrous protein that gives the epidermis its protective properties.
Melanocytes
- spider shaped epithelial cells that synthesis the pigment melanin are found in the deepest layer of the epidermis.
- Form a pigment shield that protects the nucleus from the damaging effects of ultraviolet radiation in sunlight.
Dendritic cells (Langerhans cells)
- arise from bone marrow and migrate to the epidermis.
- they ingest foreign substances and are key activators of our immune system.
Tactile cells (Merkel cells)
- are present at the epidermal-dermal junction.
- function as a sensory receptor for touch.
Stratum Basale
- Deepest epidermal layer
- single row of stem cells
- 10 to 25% of cells are melanocytes.
Stratum Spinosum
- several layers thick
- contain a weblike system of intermediate filaments, mainly tension- resting bundles of pre-keratin filaments.
Stratum Granulosum
- consists of three to five layers of flattened cells
- two types of granules: keratohyaline granules and lamellar granules.
Stratum Corneum
- most superficial layer
- 20 to 30 layers of dead cells
- essentially flat membrane sacs filled with keratin
- Glycolipids in extracellular space
Describe the dermis
- strong flexible connective tissue
- has two layers: papillary and reticular layer
Which pigments contribute to skin color and what color does each add?
-Skin color is determined by the amount of melanin present.
Erythema
Reddened skin may indicate embarrassment(blushing), fever, hypertension, inflammation, or allergy.
Pallor, or blanching
- During fear, anger, and certain other types of emotional stress, some people become pale.
- Pale skin may also signify anemia or low blood pressure.
Jaundice or yellow cast
an abnormal yellow skin tone usually signifies liver disorder, in which yellow bile pigments accumulate in the blood and are deposited in body tissues.