Ch 43 Drugs affecting blood pressure Flashcards
Angiotensin converting enzyme ACE inhibitor
Drug that blocks ACE, the enzyme responsible for converting angiotension one to angiotension two in the lungs; this blocking prevents the vasoconstriction and Aldosterone release related to angiotension two
Angiotensin two receptors
Specific receptors found in blood vessels and the adrenal gland that react with angiotensin two to cause vasoconstriction and the release of aldosterone
Baroreceptor
Pressure receptor; located in the arch of the aorta and in the carotid, artery; response to changes in pressure and influences the medulla to stimulate the sympathetic system to increase or decrease blood pressure
Cardiovascular center
Area of the medulla at which stimulation will activate the sympathetic nervous system to increase blood pressure and heart rate
Essential hypertension
Sustained blood pressure above normal limits with no discernible underlying cause
Hypotension
Sustained blood pressure that is lower than that required to adequately profuse all of the bodies tissues
Peripheral resistance
Force that resists the flow of blood through the vessels, mostly determined by the arterials, which contract to increase resistance; important in determining overall blood pressure
Renin angiotensin aldosterone system
Compensatory process that leads to increased blood pressure and blood volume to ensure perfusion of the kidneys; important and the continual regulation of blood pressure
Shock
Severe hypotension that can lead to accumulation of waste products and cell death
Stroke volume
The amount of blood pumped out of the ventricle with each beat; important in determining blood pressure