Ch 29 Neuromuscular junction blocking agents

Question 1

Acetylcholine receptor site

Answer 1

Area on the muscle cell membrane where acetylcholine ACh reacts with a specific receptor site to cause stimulation of the muscle in response to nerve activity

Question 2

Depolarizing neuromuscular junction NMJ blocker

Answer 2

Stimulation of a muscle cell, causing it to contract with no allowance for repolarization and restimulation of the muscle; characterized by contraction and then paralysis

Question 3

Malignant hyperthermia

Answer 3

Reaction to some NMJ drugs in susceptible individuals; characterized by extreme muscle rigidity severe hyperpyrexia, acidosis and in some cases death

Question 4

Neuromuscular junction NMJ

Answer 4

There is a connection between a nerve and a muscle cell

Question 5

Nondepolarizing neuromuscular junction NMJ blocker

Answer 5

No stimulation or depolarization of the muscle cell; prevents depolarization stimulation by blocking the effects of acetylcholine

Question 6

Paralysis

Answer 6

Lack of muscle function

Question 7

Sarcomere

Answer 7

Functional unit of a muscle cell, composed of actin and myosin molecules arranged in layers to give the unit a striped are striated appearance

Question 8

Sliding filament theory

Answer 8

Theory explaining muscle contraction as a reaction of actin and myosin molecules when they are free to react by the Inactivation of troponin after calcium is allowed to enter the cell during depolarization

Question 9

Neuromuscular junction blocking agents

Nondepolarizing NMJ

Answer 9

Atracurium
Cisatracurium
Pancuronium
Rocironium
Vecuronium

Question 10

Neuromuscular junction blocking agents

Depolarizing NMJ

Answer 10

Succinylcholine