Ch 4

Question 1

Stains for ectomesenchymal chondromyxoid tumor

Answer 1

GFAP, S100, CD57

Question 2

What stain can you use to confirm granular cell tumor besides S100?

Answer 2

Cytoplasmic granules should stain positive for distase resistant PAS

Question 3

3 types of rhabdomyoma? How are they typed?

Answer 3

Fetal, juvenile, adult…typed on histology not age

Question 4

What is a nickname for the rod-shaped cytoplasmic crystals seen in rhabdomyoma?

Answer 4

Jackstraws lol

Question 5

Name that rhabdo type: spider cells, jackstraws

Answer 5

Adult type

Question 6

Name that rhabdo type: haphazard round/spindle cells, myofibrils, myxoid matrix, strap cells

Answer 6

fetal

Question 7

4 stains for rhabdomyoma

Answer 7

SMA, desmin, myoglobin, MYOD1

Question 8

Genetic mutation for fetal rhabdomyomas

Answer 8

PTCH1

Question 9

3 stains for lymphangioma

Answer 9

CD31, CD34, podoplanin (D2-40) stain the endothelial cells

Question 10

What are 3 syndromes linked to lymphangiomas?

Answer 10

Proteus, Turner, Down syndromes

Question 11

Gender predominance for hemangioma

Answer 11

female

Question 12

What is the most common benign tumor of the oral cavity and mobile tongue in the pediatric population?

Answer 12

hemangioma (infantile hemangioma)

Question 13

Good for your board comment: 3 stains for hemangioma…also - what stain is positive in infantile hemangioma but negative in a pyogenic granuloma/ectasia/congenital hemangioma?

Answer 13

1. CD34 2.CD31 3.ERG….GLUT1 positive in infantile, negative in the rest

Question 14

Huh, what heart medication can help a hemangioma resolve?

Answer 14

Beta blocker

Question 15

2 stains for schwannoma

Answer 15

S100, SOX10

Question 16

6 stains for KS

Answer 16

HHV8, podoplanin, CD34, CD31, FLI1, ERG