Ch. 34 Adaptive Immunity Flashcards
Adaptive Immunity is “Immunity by _________”
Exposure
B cells and T cells go through extensive screening to avoid _________.
Self-reactivity
________ immunity is also called antibody-mediated immunity and is based on antibody activity
Humoral
________ immunity is also called cell-mediated immunity and is based on action of specific kinds of T lymphocytes.
Cellular
Antigen determinant sites or the site on an antigen that reacts with specific antibody or T cell receptors.
Epitope
Antibody ________ is the strength with which an antibody binds to its antigen at a given antigen-binding site.
affinity
Type of specific immunity a that a host develops after exposure to a foreign substance.
Naturally acquired active immunity
The transfer of antibodies, e.g., mother to fetus across placenta, mother to infant in breast milk.
Naturally acquired passive immunity
Intentional exposure to a foreign material (vaccination).
Artificially acquired active immunity
Preformed antibodies or lymphocytes produced by one host are introduced into another host.
Artificially acquired passive immunity
A collection of genes that code for self/nonself recognition potential of a vertebrate. Called HLA complex in humans.
Major Histocompatibility Complex (MHC)
_________ MHC molecules found on almost all types of nucleated cells, important for organ transplantation.
Class I
_________ MHC molecules found only on antigen presenting cells. Required fro T cell communication to macrophages, dendritic cells, and B cells.
Class II
_________ MHC molecules include secreted proteins not required for self/nonself recognition.
Class III
________ activation requires binding to a specific antigen.
T cell
