Ch 30 Cardio Flashcards

1
Q

Can a QRS complex character in large animals reflect chamber enlargement?

A

NO. not sensitive or specific for ventricular enlargement

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2
Q

Why is peak blood flow in large animals with valvular heart disease difficult to estimate?

A

Because optimal doppler signals are obtained with the ultrasound beam parallel to the blood flow being evaluated. Thus the peak velocity is underestimated

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3
Q

What is the sedative of choice for large animals undergoing an ECG?

A

Acepromazine, given ahead of time

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4
Q

What is the most commonly reported congenital cardiac defect in large animals?

A

Ventricular septal defect. This can be evaluated appropriately with doppler

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5
Q

Cardiac and great vessel catheterization can determine what data?

A

-Pressure and waveforms
-Oxygen tension, saturation, content
-cardiac output

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6
Q

What does PAWP assess?

A

Pulmonary artery wedge pressure assesses left atrial mean pressure, left ventricular function, and fluid therapy

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7
Q

Describe a VSD’s character in 1-2 sentences

A

Loud, grade 4-6 plateau pansystolic murmur with PMI in tricuspid area. Murmur on the L has a PMI at the pulmonic valve area.

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8
Q

What are the characteristics of an innocent flow murmur of neonates?

A

-Crescendo-decrescendo shape
-PMI L heart base
-lack of radiation
-low-moderate intensity

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9
Q

What valvular insufficiency do horses with VSD often develop later in life?

A

Mitral regurgitation

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10
Q

What clinpath abnormality would indicate a complicated VSD?

A

polycytemia

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11
Q

Pressure increases in which chambers in animals with VSD indicate cardiac failure?

A

Increased pressure in the left or right ventricles during diastole

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12
Q

Horses with what size of VSD can still race successfully?

A

VSD must be </= 2.5 cm

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13
Q

What VSD to aortic root ratio in nonracing horses and ponies is likely hemodynamically benign?

A

ratio < 0.3

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14
Q

What metrics of a VSD would indicate reduced life expectancy and tendency to develop CHF?

A

Defect > 3.5 cm, VSD/AR ratio 0.64, peak shunt velocity < 3.5 m/s

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15
Q

What are classic signs of a PDA on cardiac auscultation?

A

-continuous machinery murmur
-loudest at L ICS 3-4 at point of shoulder level (can be heard on L or R)
-Bounding arterial pulses due to runoff of blood from systemic to pulmonary circulation
-Murmur intensity increases with exercise, excitement, inc HR

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16
Q

In foals, a PDA normally closes by what time after birth?

A

96 hours

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17
Q

What physiologic “pressures” usually make a PDA close shortly after birth?

A

-lowered pulmonary vascular resistance
-increased systemic resistance
-increased blood volume
-increased left ventricular pressure

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18
Q

A right to left shunt occurs due to what pressure balances/imbalances?

A

When pulmonary resistance equals or exceeds systemic vascular resistance

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19
Q

What are the components of Tetralogy of Fallot? What does Pentalogy include?

A
  1. Overriding aorta
  2. VSD
  3. Obstructed pulmonary arterial flow
  4. 2* R ventricular hypertrophy
  5. ASD or PDA
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20
Q

Cyanosis is noticed when ______ g/dL of hemoglobin are reduced/unoxygenated

A

> 5

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21
Q

What common ER treatment for respiratory distress is unhelpful in patients with R to L shunts?

A

Oxygen administration

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22
Q

What clinpath abnormalities may be seen in animals with Tet or Pent of Fallot?

A

Increased PCV, RBC, and polycytemia

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23
Q

A client has a yearling with tetralogy of fallot. she wants to know, is this condition heritable?

A

No. Or at least no evidence yet to say that

24
Q

How does an atrial septal defect usually sound on auscultation?

A

holosystolic, crescendo-decrescendo at the left heart base (because more volume is being ejected across the pulmonic valve)

25
What abnormalities are associated with tricuspid valve atresia in foals?
Patent foramen ovale, small R ventricle, large L ventricle, large mitral valve orifice
26
Which clinical sign would help distinguish persistent truncus arteriosis from VSD or PDA?
Cyanosis
27
Persistence of what structure can cause esophageal compression?
Right aortic arch or double aortic arch
28
What abnormalities are part of the Eisenmenger complex?
VSD, overriding aorta, dilated pulmonary trunk
29
What is your top differential for an older horse with recent-onset machinery murmur that is loudest on the right? What if the horse was a Friesian?
Aorticocardiac fistula. In Friesians, suspect aortopulmonary fistula
30
What cardiac changes might you hear in a foal whose PDA has closed? For how long would you expect to hear this?
Loud systolic ejection murmur at the L heart base. May persist for 2-3 mo
31
What are the most common bacterial isolates from equine and bovine endocarditis?
Equine: Streptococcus, Pasturella Bovine: Actinobacillus or Trueperella pyogenes
32
In general, how do valvular murmurs sound?
Radiating from the PMI in the direction of the ABNORMAL blood flow, coarse and band-shaped, crescendo or musical/honking is systolic, and diastolic are decrescendo and blowing/dive-bomber sounding. Usually moderate-loud
33
In which type of valvular equine murmur is murmur intensity a reliable indicator of lesion severity?
Tricuspid regurgitation. Longer, louder murmurs = larger jet
34
Mumurs of which outflow valves are most common in cattle vs horses?
Equids: aortic regurgitation Cattle: pulmonic regurgitation secondary to bacterial endocarditis
35
What signs distinguish murmurs due to ruptured mitral valve chordae tendinae?
-Widely radiating, musical sound -Honking sound or band-shaped pansystolic murmur -Acute hemodynamic collapse -Respiratory signs Pulmonary edema
36
What qualities would be characteristic of a mitral valve prolapse?
Crescendo midsystolic to late systolic or holosystolic murmur over the mitral valve area
37
____ is an echocardiographic indicator of increased severity of the aortic regurgitation
Decreased aortic root diameter during diastole
38
Which condition of horses is most closely associated with (causes) tricuspid valve bacterial endocarditis?
Septic jugular vein thrombophlebitis
39
What causes and contributes to cor pulmonale in cattle?
Primary cause: altitude/high mountain disease (hypoxic vasoconstriction) lead to pulmonary hypertension and RV hypertrophy/dilation or failure. Worsened by pneumonia, lungworm, prolonged cold exposure, and by ingesting Locoweed (Astragalus and Oxytropis)
40
What causes tricuspid regurgitation in cor pulmonale?
right ventricular dilation due to R sided failure
41
What common sign of respiratory disease is NOT commonly present with cor pulmonale?
Pleural or pericardial effusion
42
Which echocardiographic finding is relatively sensitive for pulmonary hypertension?
Pulmonary artery dilation
43
Which conditions/characteristics predispose cattle to developing HMD?
Living at altitudes > 6000ft, genetics unused to altitude, younger age of animal, ingesting Oxytropis and Astragalus spp plants, cold weather, ionophores in feed
44
Cattle with pulmonary arterial pressure values of _____ are suitable for grazing at altitude?
PAP < 41 at over 5000 ft elevation. If at > 49, they are at greater risk
45
What are the recognized bacterial causes of myocarditis? Viral? Parasitic?
Bacterial: Staph aureus, Strep equi, Clostridium chauvoei, and Mycobacerium spp Viral: EVA, EIA, equine influenza, African horse sickness, FMD Parasitic: strongylosis, onchocerciasis, toxoplasmosis, cystercercosis, sarcosystic infection
46
Ingestion of what agents is associated with development of cardiomyopathy?
Monensin, lasalocid, salinomycin, gossypol, Cassia occidentalis, Phalaris spp., molybdenum excess, Bonus: Acer family plants cause myocardial injury
47
What mineral/vitamin derangement are associated with cardiomyopathy?
Selenium and vitamin E defic, Cu deficiency, excessive molybdenum, high sulfates.
48
During what part of the production cycle are cattle most at risk of developing dilated cardiomyopathy?
Within 3 months of calving
49
What is the toxic component from Acer spp plants?
Hypoglycin A.
50
Which chemistry enzymes change with monensin toxicosis?
CK and LDH elevate
51
If a cow presents with signs of myocardial disease, what should she be tested for?
Serum: leukosis virus, alpha tocopherol, glutathione peroxidase, and copper concentrations Whole blood: selenium,
52
Hemoglobinuria concurrent with cardiomyopathy suggests which differential diagnoses?
Monensin, gossypol, nutritional myodegeneration,
53
What echo changes are seen in animals with sustained VT and decreased cardiac output?
Small LV internal diameter, thickened LV free wall and interventricular septum, small aortic root diameter, decreased FS
54
What change is seen on echo that can differentiate hypertensive cardiomyopathy from sustained VT?
increased relative mean wall thickness and RV free wall, as well as decreased myocardial function
55