Ch 3 Embryogenesis and Development Flashcards
Different types of twins
Dizygotic (fraternal) form from fertilization of 2 different eggs released during 1 ovulation cycle by 2 different sperm. Monozygotic (identical) form when single zygote splits into 2 - genomes identical
2 types of cleavage
Indeterminate results in cells then can still develop into complete organisms. Determinate results in a specific, pre fated type of cell
Divisions of cleavage
Zygote - embryo - morula - blastula - gastrula
Blastocyst cell groups
Trophoblast - chorion & placenta
Inner cell mass - organism
Chorion
Extraembryonic membrane that develops into the placenta
Umbilical cord connects
Placenta to embryo
Umbilical vein and artery
Vein carries O2 blood to embryo
Artery carry deoxygenated blood and waste to placenta for exchange
Amnion
Incases amniotic fluid for shock absorption
Opening of gastrulation invagination results in
A blastopore, which in deuterostomes develops into anus
Gastrulation results in primary germ layers - describe
Ectoderm - integument and nervous system
Mesoderm - musculoskeletal, circulatory, excretory, gonads, connective tissue
Endoderm- digestive and respiratory, lining of internal organs
Induction
Ability of one group of cells to influence nearby cells - related to selective transcription. Mediated by inducers (chemicals)
Dual embryonic origin of adrenal glands
Adrenal cortex is mesoderm
Adrenal medulla is ectoderm (nervous tissue)
Notochord
From mesoderm. Induces neurulation which gives rise to CNS via neural tube
Neural crest cells
Gives rise to PNS
Cell specialization
- Specification - designated as specific cell type
- Commitment of cell to a future function(irreversible)
- Differentiation - undertake changes that allow the cell to become a specific cell type
Stem cells
Cells that have not yet differentiated or give rise to cells that will differentiate
Potency in cell differentiation
Totipotent- greatest potency can differentiate into any cell type in fetus or placenta (embryonic mainly)
Pluripotent- any cell type except those found in placental structures
Multipotent - intuitions cell types within a particular group
Cell signaling
Autocrine - act in same cell that secreted signal
Paracrine - act in local area (diffusion)
Juxtracrine- direct cell contact
Endocrine - hormone through bloodstream
Cell inducers (signaling) are often
Growth factors
To assist with O2 transfer, fetal blood cells have
HbF, which has a greater affinity for O2 than adult Hb
Umbilical artery vs vein
Umbilical artery carries blood away from fetus to placenta. Umbilical vein is blood toward fetus from placenta
Fetus does not depend on lungs and liver, as these functions occur at placenta. Fetus constructs 2 shunts to direct blood away from these organs while they develop
Foramen ovale - one way that connects right atrium to left atrium, bypassing blood to the lungs.
Ductus arteriosus - shunts blood from pulmonary artery to aorta, by passing lung
Ductus venosus - shunts blood from umbilical vein to inferior vena cava, by passing liver
First trimester
Major organogenesis, brain mostly developed, bone formation, limbs, after 8 weeks knows as fetus