Ch 3-5 Urinary Tract Imaging Flashcards
Current unit of radiation exposure
Coulombs (C)/kg
Energy absorbed from the radiation exposure
Absorbed dose
Measured in gray (Gy)
The older unit of absorbed dose
Rad (1 rad =100 Gy)
Application of conversion factor to the absorbed dose
Equivalent dose
Measured in sieverts (Sv)
Effective dose is defined as
Quantity used to denote radiation risk (expressed in sieverts)
What is the recommended occupation exposure limit to medical personel?
50 mSv per year
Reduction in radiation exposure to medical personnel is achieved by? (3)
(1) limiting the time of exposure; (2) maximizing distance from the radiation source; and (3) shielding.
Mechanisms of Allergic-like Reactions (ALR)
(1) release of vasoactive substances including histamine
(2) activation of physiologic cascades, including complement, kinin, coagulation, and fibrinolytic systems
(3) inhibition of enzymes including cholinesterase, which may cause prolonged vagal stimulation
(4) the patient’s own anxiety and fear of the actual procedure
Delayed contrast reactions can occur from _______
3 hours to 7 days after administration of contrast
14-30% after injection of ionic monomers
8-10% after the injection of nonionic monomers
Incidence of 0.5-9%
TRUE or FALSE: Do those with previous ALR (allergic like reaction) have a risk of developing future ALR?
YES - 5-fold increased risk of developing future ALR
TRUE or FALSE: If with other type of allergies, is there an increased risk of ALR?
TRUE - 2-3x increased risk for ALR
But those w shellfish and iodine allergies are at NO GREATER RISK
How does anxiety affect contrast reactions?
More commonly occur in those w anxiety; may need reassurance but NO PREMEDS
What are other risk factors for contrast reactions?
- Asthma
- Beta-blockers
- Cardiac abnormalities
- Hyperthyroidism
- Myasthenia Gravis
- Sickle cell trait / disease
What is the surmised pathophysiology of post-contrast AKI?
- Vasoconstriction
- Direct tubular toxicity
- Osmotic mechanisms
- Chemotaxic mechanisms
Defined as one of the following occurs within 48 hours after administration of iodinated contrast medium: increase in serum creatinine of >0.3 mg/dL, >50% increase in serum creatinine from baseline, or urine output reduced to <0.5 mL/kg/h for at least 6 hours
Contrast induced nephropathy
Metformin should be discontinued day of study and withheld 48 hrs after due to risk of _____
Biguanide lactic acidosis
— Metformin stimulates intestinal production of lactic acid thus causing accumulation in those w Type 2 DM and impaired renal function
Do you need to discontinue Metformin before gadolinium studies?
No when the amount used is 0.1 to 0.3mmol/kg of body weight
Nephrogenic systemic fibrosis is related to what contrast medium
Gadolinium
— seen in those w severe renal dysfunction
Extracellular MRI agents can interfere with which serum assays:
Calcium, Iron, Magnesium, TIBC, Zinc can all have spurious results
Biochemical assessment is more reliable 24hrs after
What is a necessary factor in the development of nephrogenic systemic fibrosis?
Exposure to Gadolinium
Whistle tip, spiral tip, and open ended catheters are classified as what type of catheters?
NON-OBSTRUCTING catheters
Bulb tip, cone tip, wedge tip catheters are what kind of catheters?
OBSTRUCTING URETERAL CATHETERS
Mechanisms of attenuation in ultrasound
(1) Reflection
(2) Scattering
(3) Interference
(4) Absorption
Physical phenomenon that allows for information to the return to the transducer as mechanical energy
Reflection
Amount of energy reflected from an interface is influenced by _____, which is influenced by tissue stiffness and density
Impedance
Occurs when mechanical energy of the ultrasound waves is converted to heat; it is directly proportional to frequency
Absorption
Also known as PENTETIC ACID
Diethylenetriaminepentaacetic acid (DTPA)
Nuclear imaging scan used to assess functional renal obstruction
It is also extracted by the kidneys entirely by glomerular filtration
DTPA scan
Radiotracer excreted by urine to determine renal split function; and assess for functional obstruction
Cleared by TUBULAR SECRETION
MAG3 (Mercaptoacetyltriglycine)
Agent of choice for measuring the differences between RPF and assessing functional obstruction
MAG3
Radiotracer that undergoes receptor-mediated endocytosis by the proximal tubular cells
DMSA
Radiotracer best suited for imaging cortical processes (ex. Acute pyelonephritis, renal scarring)
DMSA (Dimeracaptosuccinic acid)