CH 3 Flashcards

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1
Q

List the main component of the plasma membrane and what it is made out of. List the property of each part as well as the component as a whole.

A

Phospholipids. They have a phosphate head and two fatty acid tails. Phospholipids are amphiphilic. The phosphate head is hydrophilic and polar and the fatty acid tails are hydrophobic and non polar

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1
Q

What is the plasma membrane

A

Plasma Membrane - phospholipid bilayer and embedded proteins which separate the intracellular environment from the extracellular environment.

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2
Q

What are the phosphate heads and fatty acid tails made up of?

A

Phosphate heads - Made up of Glycerol and Phosphate Group
Fatty Acid Tails - Made up of long chains of carbon and hydrogen.

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3
Q

Describe the differences between hydrophobic, hydrophilic, amphipathic/amphiphilic, nonpolar and polar molecules.

A

Hydrophilic – having the tendency to be attracted to and dissolve in water.
Hydrophobic - having the tendency to repel and be insoluble in water.
Amphipathic/ Amphiphilic - describes molecules with both hydrophilic and hydrophobic components. (Such as phospholipids)
Polar - describes a molecule with both a positive end and negative end. These tend to be hydrophilic.
Nonpolar - describes a molecule without a clearly positive or negative end. These tend to be hydrophobic.

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4
Q

List and describe the three types of proteins.

A

Integral Protien – proteins that are a permanent part of the membrane.
- Transmembrane Protien – integral proteins that go through the entire bilayer.
Peripheral Protien – protiens that are temporarily attached to the plasma membrane and only interact with the phosphate heads of phospholipids.

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5
Q

List the 4 functions of proteins

A

Transport –channels or pumps in a protein that control what enters and exits the cell, making the plasma membrane selectively permeable.
Catalysis – speeding up chemical reactions with the help of a protein group called enzymes.
Communication – receive signals or recognise cells and molecules. Often attached to the cytoskeleton to transmit signals into the cell.
Adhesion – stick to other cells, the extracellular matrix, or the cytoskeleton.

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6
Q

What is the function and structure of a Carbohydrate? Also describe the two types of carbohydrates.

A

Structure:
-Chain structure that extends outside the cell that is rooted in the membrane.
-Glycolipids – a carbohydrate bound to a phospholipid.
-Glycoprotien - a carbohydrate bound to a protein.
Function:
-Aids with cell-to-cell communication, signalling, recognition of self or non-self (foreign) molecules, and adhesion.

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7
Q

What is the function and structure of a Cholesterol? Also what is cholesterol?

A

Cholesterol – a steroid-alcohol that regulates fluidity in plasma membranes.
Structure:
-A lipid steroid that embeds itself between the fatty acid tails of the phospholipid bilayer in animal cells. Other kingdoms have similar molecules with similar functions.

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8
Q

What is the function of cholesterol?

A

Function:
-Regulates the fluidity of the membrane.
-At higher temperatures, the cholesterol keeps phospholipids bound together as cholesterol has hydrophobic regions which can increase nonpolar interactions with the tails.
-At lower temperatures, cholesterol disrupts the fatty acid tails, stopping phospholipids from becoming a solid boundary by taking up room in the membrane which prevents it from packing too tightly.

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9
Q

What is the Fluid Mosaic model and explain each part.

A

Fluid Mosaic Model - the theory of how the plasma membrane is structured.
‘Fluid’ Explains that:
-Phospholipids continuously move. This allows the plasma membrane to be fluid.
-Phospholipids can rotate, move laterally or transverse.
‘Mosaic’ Explains that:
-Protein and Carbohydrates embedded in the membrane are able to move around fluidly in the bilayer.
-Scientists imagine that it would look like mosaic pictures.

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10
Q

What are two words to describe membrane fluidity and explain what they mean.

A

-Saturated - fatty acid chain with only single bonds between carbon atoms. This allows phospholipids to pack together tightly as the tails have no kinks.
-Unsaturated - fatty acid chain with at least one double or triple bond between carbon atoms. This pushes phospholipids apart as the tails have many kinks.

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11
Q

What is passive transport?

A

Passive Transport - the movement of molecules through a semipermeable membrane and down the concentration gradient, without an input of energy.

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12
Q

Diffusion vs Simple Diffusion.

A

Diffusion - the passive movement of molecules from areas of high concentration to areas of low concentration (down the concentration gradient) due to kinetic energy.

Simple Diffusion – small and nonpolar molecule diffusion through a phospholipid bilayer (e.g., oxygen and carbon dioxide)
-Once equilibrium is reached the solute moves equally in both directions.

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13
Q

List 2 Factors that affect simple diffusion and define an ion.

A

Size – small, nonpolar molecules are able to slip through the bilayer. Highly charged molecules such as ions are not able to cross despite their size.
Polarity: nonpolar, uncharged, or hydrophobic molecules are able to cross as the plasma membrane is mostly nonpolar due to the fatty acid tails that attract them.
Ion – atom or particle with an electric charge due to the loss or gain of electrons.

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14
Q

Solute vs Solvent

A

Solute - a substance dissolved in the solvent.
Solvent - a liquid in which a solute is dissolved, forming a solution.

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15
Q

What is Facilitated Diffusion?

A

Facilitated Diffusion - a type of passive transport where molecules move through a phospholipid bilayer with the aid of a membrane protein. These proteins are specific to the type of molecule they transport. Some small or nonpolar molecules (e.g., water) also have dedicated protein channels.

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16
Q

What are protein channels?

A

Protein Channel - transmembrane protein pore in a phospholipid bilayer that selectively enables transport of large or polar molecules.
-The channel provides a hydrophilic passageway for those molecules.

17
Q

What are carrier proteins and what is the process they undergo?

A

Carrier Protein - membrane protein that undergoes conformational change to transport molecules across a membrane. Organic molecules tend to use carrier protein to diffuse.
-The molecule binds to the protein which then stimulates the protein to change shape and push the substance down to the other side.
-Conformational Change - change in the three-dimensional shape of macromolecules such as proteins

18
Q

What are water-specific protein channels called?

A

Aquaporins

19
Q

What is Osmosis?

A

Osmosis - the passive transport of a solvent (typically water) through a selectively permeable membrane from a region of low solute (high solvent) to a region of high solute (low solvent)

20
Q

What is Osmolarity?

A

Osmolarity – total concentration of solutes in a solution. A cell in a solution with high osmolarity is said to be hypertonic and vice versa with low osmolarity.

21
Q

What is tonicity?

A

Tonicity - the measure of the difference in concentration of solutes on either side of a semipermeable membrane, described as hypertonic, hypotonic, or isotonic.

22
Q

What are hypotonic solutions?

A

Hypotonic Solutions – Solutions that have comparatively low solute concentrations, so water moves from a hypotonic solution into adjacent areas with a higher solute concentration.

23
Q

What are hypertonic solutions?

A

Hypertonic Solutions – Solutions that have comparatively higher solute concentrations, so water moves into a hypertonic solution from adjacent areas with lower solute concentrations.

24
Q

What are isotonic solutions?

A

Isotonic Solutions – Solutions that have equal solute concentrations, so there is no net movement of water. The rate of water moving in is equal to the rate of water moving out, is equal.

25
Q

In plant cells:
What happens when the extracellular fluid is hypertonic compared to the cytosol?
What happens when the extracellular fluid is hypotonic compared to the cytosol?
What happens when the extracellular fluid is isotonic compared to the cytosol?

A

Hypertonic:
- Plant cells do not burst due to the cell wall and are considered Turgid. (Normal)
- Turgid describes plant cells that are swollen and firm from water intake.
Hypotonic:
- Plant Cells shrink and become plasmolysed.
- Plasmolysed describes plant cells with a weak and sagging plasma membrane due to water loss.
Isotonic:
-Plant cells are considered Flaccid.

26
Q

In Animal cells:
What happens when the extracellular fluid is hypertonic compared to the cytosol?
What happens when the extracellular fluid is hypotonic compared to the cytosol?
What happens when the extracellular fluid is isotonic compared to the cytosol?

A

Hypertonic:
- Animal cells swell until they burst/Lyse.
- Lyse - to cause a plasma membrane to burst or break.
Hypotonic:
- Animal Cells become shrivelled.
Isotonic:
- Animal Cells are considered normal.

27
Q

What is active transport?

A

Active Transport - the movement of molecules across a semipermeable membrane that requires energy.

28
Q

What is protein-meditated active transport?

A

Protein-Mediated Active Transport/Active Transport – a type of active transport that involves using membrane proteins to move molecules across a membrane against their concentration gradient.
-This process can be used to control water movement as pushing solutes into a high concentration area can force osmosis to passively occur.

29
Q

What molecules are required for protein-meditated active transport?

A

The Molecules Require:
-Energy usually in the form of adenosine triphosphate (ATP).
-Membrane Proteins, typically protein pumps or carrier proteins.

30
Q

What is the process of protein-meditated active transport?

A

Process:
-Binding – molecule binds to the specific protein pump.
-Conformational Change – energy is released causing conformational change in the protein pump.
* (From the reaction: ATP -> ADP + Pi).
* Energy comes from breaking the bond between the second and third phosphate ions in the ATP molecules.
-Release – the molecule is pushed through and released to the other side of the membrane.

31
Q

What is ATP and what are 2 parts called?

A

Adenosine Triphosphate (ATP) - high energy molecule that, when broken down, provides energy for cellular processes.
ADP – Adenosine Diphosphate
Pi – Inorganic Phosphate

32
Q

What is bulk transport/Cytosis?

A

Bulk Transport/Cytosis - a type of active transport that uses vesicles to move large molecules or groups of molecules into or out of the cell.

33
Q

What is a protein pump?

A

Protein Pump - polypeptide that transports molecules across a membrane against its concentration gradient with the aid of ATP.

34
Q

What is exocytosis? What organelle uses this process?

A

Exocytosis - a type of bulk transport that moves large substances out of the cell.
Golgi Apparatus used exocytosis to export proteins.

35
Q

What is the process of exocytosis?

A

Process:
-Vesicular Transport – a vesicle containing secretory products is transported to the plasma membrane.
-Fusion – the membranes of the vesicle and cell fuse.
*This is possible due to the fluidity of the membrane.
*The vesicle adds phospholipids to the bilayer and makes the surface area bigger when fusing.
-Release – the secretory products are released from the vesicle and out of the cell.

36
Q

What is endocytosis? What organelle uses this process?

A

Endocytosis - a type of bulk transport that moves large substances into the cell.
- Lysosomes often use endocytosis to enter a cell with toxins or invaders to digest them.

37
Q

What is the process of endocytosis?

A

Process:
- Fold – the plasma membrane folds inwards to form a cavity that fills with extracellular fluid and the target molecules.
- Trap – the plasma membrane continues folding back on itself until the two ends meet and fuse. This traps the molecule inside.
*This takes phospholipids away from the plasma membrane.
*In large amounts of endocytosis, the cell could shrink.
- Bud – the vacuole/vesicle (or endosome) pinches off the membrane. It is then transported to an appropriate location or fused with a lysosome for digestion.

38
Q

What are the two types of endocytosis?

A

Phagocytosis - endocytosis of solid material or food particles
Pinocytosis - endocytosis of liquid or dissolved substances

39
Q
A

Vesicles - a small membrane-bound sac that transports or stores substances within a cell.
Secretory Products - the substances inside a vesicle that are being transported out of the cell.