Ch 24 Flashcards

1
Q

Metabolic bone disease characterized by low bone mass leading to bone fertility and consequently an increase in risk of fracture

A

Osteoporosis

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2
Q

a bone density below normal but not as low as a diagnosis of osteoporosis

A

Osteopenia

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3
Q

Impaired mineralization caused by calcium and vitamin D deficiency (symptoms are fractures that occur without injury)

A

Osteomalacia

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4
Q

Caused by a force less than or equal to that of a fall from standing height also known as non-traumatic fracture

A

Fragility fracture

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5
Q

Found in the knobby ends of long bones (iliac crest pelvis wrist scapula vertebrae)
is more responsive to estrogens or lack of estrogen

A

Trabecular bone

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6
Q

Found in shops of the long bones and compromises 80% of the skeleton

A

Cortical bone

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7
Q

Measurement of the density of bone

A

Bone mineral density BMD

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8
Q

Average bone density of the US population of premenopausal women

A

Zero

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9
Q

Cells that form or produce bone tissue

A

Osteoblast

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10
Q

Cells that are in charge of bone resorption

A

Osteoclasts

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11
Q

Needed calcium intake per day 10-50 yrs old

A

1000 mg

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12
Q

Calcium requirements for adults over 51 or for pregnant and nursing mothers

A

1200 mg

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13
Q

Calcium requirements for teens 9 to 15

A

1300 mg

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14
Q

Calcium requirements for children want to 10 years old and infant seventh to 12 months

A

800mg

270 mg

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15
Q

2 forms of vitamin D

A

Total 50-OH hydroxyvitamin D

1,25 dihydroxyvitamin D

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16
Q

Form of vitamin D that is by prescription only for renal patients and is potent

A

1,25-OH dihydroxyvitamin D

17
Q

2 types of 25-Oh dihydroxyvitamin D

A

Vitamin D3 and vitamin D2

18
Q

Cholecalciferol , in fish/meat

A

Vitamin D3

19
Q

Ergocalciferol

A

Vitamin D2

20
Q

Benefits bone cells , improve muscle strength , regulates immune system , and prevention of breast prostate or colon cancer

A

Vitamin D3

21
Q

Lack of vitamin D will cause a ____ in parathyroid hormone

A

Increase

22
Q

Vitamin D. Deficiency

A

<20 ng/ml

23
Q

Vitamin D insufficiency

A

21-29

24
Q

Adequate vitamin D

A

> 30 ng/ml

25
Q

Vitamin D intoxication

A

> 150 ng/ml

26
Q

2 Ways osteoporosis is diagnosed

A

Osteoporotic fracture and low bone density measurement

( T-score

27
Q

Primary osteoporosis

A

Age related / postmenopausal

28
Q

Caused by another medical condition or use of a medication

A

Secondary osteoporosis

29
Q

T score of +1 to -1

A

Normal BMD

30
Q

T score of -1 to -2.5

A

Osteopenia

31
Q

Tscore

A

Osteoporosis

32
Q

Recommended vitamin D intake

A

800 to 1000 IU

33
Q

Pharmacological treatment for osteoporosis

A

Estrogen replacement therapy (Tscore of -2)

34
Q

Stops osteoclasts from breaking down bone

A

Biophosphonate’s

35
Q

Anti-bone resorption agent for women only improves lipid profile protective against breast cancer

A

Raloxafene

36
Q

Daily injections
form of parathyroid hormone
stimulates new bone formation
very expensive

A

Forteo injections