Ch. 23 Flashcards

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1
Q

varicocele

A

enlargement of veins within the loose bag of skin that holds testicles

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2
Q

Round-headed sperm

A

sperm lack the tip (acrosome)
autosomal recessive form of male infertility (RARE)

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3
Q

Why does female infertility increases with age

A

older women produce oocytes that have abnormal chromosome # (aneuploid) = spontaneous abortion bc defects are too severe

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4
Q

In vitro fertilization

A

sperm fertilizes an oocyte in culture dish, works if ovaries and uterus work but uterine tubes are blocked

can only transfer ONE OR TWO embryos at a time

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5
Q

First IVF child

A

Louise Joy Browne

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6
Q

Preimplantation Genetic Diagnosis (PGD)

A

detection of genetic and chromosomal abnormalities prior to implantation to prevent baby from getting disease

1 blastomere removed for testing

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7
Q

Polar Body Analysis

A

provides genetic info earlier in development, before fertilization

genetics are different in polar bodies

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8
Q

___ reproductive technologies may replace the source of a male or female gamete, aid fertilization, or provide a uterus.

A

assisted

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9
Q

Individuals and couples who can conceive a child unaided, but for whom conception may take longer than usual are

A

subfertile; Subfertility occurs when it takes longer than usual to conceive a child.

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10
Q

The inability to conceive a child after a year of frequent intercourse is i

A

infertility

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11
Q

As a woman ages, her fertility ___, and her risk of pregnancy-related problems ____.

A

decreases; increases

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12
Q

To test for male infertility, what aspects of fertility can be analyzed?

A

sperm count, motility, and morphology.

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13
Q

Place the steps involved in in vitro fertilization in the correct sequence.

A
  1. oocytes are first collected from an ovary.
  2. transferred to a culture dish containing chemicals similar to those in the female reproductive tract.
  3. Sperm can either be added directly to the culture dish or microinjected into the female cell.
  4. one blastocyst is transferred to the uterus.
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14
Q

In preimplantation genetic diagnosis, what is the source of the DNA used for genetic testing?

A

a cell from an embryo; a single cell is removed from an 8-cell embryo

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15
Q

In terms of selecting an embryo that does not have a certain recessive disease, sequential polar body analysis is only useful

A

when the mother is a carrier for the disease; Only women make polar bodies, and if the woman had the disease, both her ovum and her polar body would carry disease alleles. Therefore, the only way polar body analysis is useful is if the mother is heterozygous for the disease allele.

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16
Q

Assisted reproductive technologies were developed to treat _________blank but are increasingly included in _________blank.

A

infertility; genetic testing

17
Q

Subfertility means

A

a couple will get pregnant more slowly than average.

18
Q

Immunological infertility can result when a man’s sperm comes into contact with his immune system. This may happen during testicular injury or surgery, or during a prostate gland infection.

Which of the following mechanisms of infertility do you predict comprises immunological infertility?

A

IgA antibodies covering sperm and preventing them from binding to oocytes