Ch 22 Flashcards
Basophils
Circulate blood
Two pro-inflammatory chemical-secreting cells
Basophils
Mast cells
Bacteria
Single called
1-2 micrometers
Inflammation
Release of chemicals
Vasodilation
Recruitment of immune cells
Delivery of plasma proteins
Vaccines produce
Artificially acquired active immunity
Antibody titer
Antibody concentration in the blood
Cytotoxic T cell
Destroys infected cells with apoptosis
Plasma cell
Produce antibodies
5 day lifespan
Spent in lymph nodes
Helper T cell
Releases interleukins and cytokines to stimulate other cells
Humoral immunity
Antibody-mediated immunity
Phagocytes
Macrophages
Neutrophils
Active immunity
Development of memory cells
Direct contact with antigen
Immune surveillance
Natural killer cells are able to detect unhealthy cells
Opsonization
Marking a target for phagocytosis
Facilitated by interaction of Fc region of antibody with a phagocyte
Antigenic determinant
Binding site
Part of immune system recognizes and binds to foreign molecule
Aka epitope
Prions
Small fragments of infectious proteins that cause disease in nervous tissue
Immunocompetent
Lymphocytes able to bind and respond to an antigen
Eosinophils
Most effective to attack multicellular parasites such as tapeworms
Adaptive immunity
Delayed response
Acquired
Complement refers to a group of
&facilitate inflammation by
Plasma proteins
Activating basophils and mast cells and by attracting macrophages and neutrophils
Pyrogens
Act on hypothalamus
Release PGE2
Viral capsids made from
Capsomeres
Lysis
Release of non enveloped virus
Oncovirus
Mammalian viruses capable of starting tumors
Latent virus
Alternating periods of activity with symptoms and no symptoms with inactivity
Viral spikes
Attach to viral capsid and envelope
Uncoating
Dissolving envelope
Capsid releases nucleic acid
Lysogeny
Viral genome inserting into bacterial host chromosome
Cytokines
Proteins
Serve as chemical messengers
Virus
Composed of nucleic acid within a protein capsid
Cytotoxic T-lymphocytes destroy infected cells by releasing
Perforin and granzymes
Antibodies
Effectors of humoral immunity
Secondary response of immune system involves
More cells than the antigen challenge
Due to proliferation of memory cells
IgM
Pentamer
Agglutination of mismatched blood
IgA
Found in tears, saliva, mucus
IgG
Most prevalent antibody in blood and lymph
As T-lymphocytes leave the thymus they are
Naive and immunocompetent
Bovine spongiform encephalopathy
Consuming meat that has been infected with a prion can lead to this
Interferon
Released by virus infected cell to prevent the spread of infection
Mast cells
Resemble basophils
Found in CT and close to small blood vessels
Kinins
Proteins
Produced by a variety of cells
Increase capillary permeability
Increase CAM production in endothelium
Stimulate pain receptors
Antigen presentation
Antigen displayed on surface of cell so T-lymphocyte can be exposed to it
Membrane attack complex
Forms a channel in the target cell membrane that causes cytolysis
Neutralization
Antibody covers a specific region of virus to bind to cell receptor
Fever
Inhibits reproduction of bacteria
Increases CAMs in the endothelium and capillaries of lymph nodes