ch 20 digestion Flashcards

1
Q

what organ is the liver connected to

A

gallbladder

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2
Q

what does the liver produce?

A

bile

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3
Q

where is bile stored?

A

the gallbladder

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4
Q

what controls bile release during digestion

A

the duodenum, using a sphincter

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5
Q

what is the main cell in the liver

A

hepatocytes

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6
Q

what carried the absorbed nutrients to the liver?

A

hepatic portal vein

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7
Q

what are Kupffer cells

A

resident immune cells that break down old/damaged cells and attack bacteria that may enter from the GI tract

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8
Q

what 2 energy functions does the liver perform?

A

Glycogenesis/Glycogenolysis and lipolysis/lipogenesis

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9
Q

what is glycogenesis

A

the conversion of :
glucose to glycogen (storage)

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10
Q

what is Glycogenolysis

A

the conversion of : glycogen to glucose (use)

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11
Q

what is lipolysis

A

converting fatty acids to acetyl-CoA (to make ATP)

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12
Q

what is lipogenesis?

A

glucose or amino acids to triglycerides
(energy storage)

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13
Q

what is Gluconeogenesis:

A

making glucose from glycerol in triglycerides, certain amino acids or lactate

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14
Q

what does the liver store?

A
  • excess fat soluble vitamins (KADE)
  • minerals and trace metals
  • Glycogen (for eventual hydrolysis during fasting/exercise)
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15
Q

what does the liver break protein waste products into

A

urea

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16
Q

what is albumin used for

A

osmotic regulation

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17
Q

what are complement proteins for

A

immune component reaction

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18
Q

what is fibrinogen for

A

required for blood clotting

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19
Q

what is angiotensin for

A

precursor of renin-angiotensin system for blood pressure)

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20
Q

what vitamin does the liver activate

A

vitamin D

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21
Q

what are the salivary enzymes that begin digestion

A

amylase and lipase

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22
Q

what happens because of stomach’s low pH

A

denatures proteins
pepsin begins breaking into short peptides

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23
Q

pancreas enzymes will break down what 4 things

A

carbohydrates
fats
proteins
nucleic acids

24
Q

T or F: humans cant absorb disaccharides

A

TRUE
they need to be broken down (by enzymes) into monos

25
what is used to break down fat
bile (emulsifies)
26
what are the 2 enzymes that break down nucleic acids
RNase and DNase
27
what enzymes break proteins into small peptides
trypsin and chymotrypsi
28
what breaks peptides into individual amino acids
carboxypeptidase and other peptidases
29
what are villi for? where are they found
in the small intestine to inc surface area
30
what are the two layers of the epithelia
apical and basolateral
31
how are glucose and galactose absorbed thought the epithelia (both membranes)
apical -cotransport with Na+ basolateral -glucose transporter
32
how is frusctose transported through the epithelia
glucose transporter (through both membranes)
33
how are small peptides and individual aminos absorbed
sp -cotransport w H+ aa -cotransport with Na+
34
what are the two ways that water can move through cells
osmosis and facilitated diffusion
35
what signals calcium channel production
vitamin D
36
how are water soluble vitamins absorbed?
cotransport with Na+
37
which vitamins is the absorption exception
B12 -requires intrinsic factor
38
what do degraded triglycerides form
micelles -polar outside, non-polar inside
39
what are chylomicrons
a type of lipoprotein leave basolateral membrane (exocytosis) to travel through the lymph vessels
40
what are chylomicrons made of?
Triglycerides, fat-soluble vitamins, cholesterol and phospholipids along with protein
41
how are chylomicrons used by the liver
to make low density lipoproteins (to transport fat to adipose tissue)
42
up to what number of carbons can short/medium chain fatty acids diffuse into the bloodstream?
<12 carbons
43
how are most fats and fat-soluble vitamins transported to the liver
the lymphatic system
44
what happens if your gut's epithelial mucosa is damaged?
free triglycerides can enter the bloodstream instead of the lymph
45
what substances can damage intestinal epithelial cells
excessive alcohol, inflammatory disease, some non-steroidal anti-inflammatories, infections
46
T or F humans can digest fibre
FALSE humans cannot. it has a different bond than starch/glycogen
47
what is the thermogenic effect
burning some calories in order to digest food
48
what are the 3 phases of digestion
1. cephalic phase (preparation) 2. gastric phase (food entering stomach) 3. intestinal phase (food entering duodenum)
49
what initiates the cephalic phase?
the sight, smell, or thought of food
50
what does actually tasting food do?
increases gastric and gut motility
51
cephalic phase starts with the ____ NS signaling the secretion of gastric juices. this happens in _____ of digesting food
parasympathetic anticipation
52
what is motility?
GI tract smooth muscle cells contracting to move food along using peristaltic contractions
53
when does the gastric phase begin
when food enters the stomach
54
what is created during the gastric phase
chyme -food mixed with stomach acid
55
when does the intestinal phase begin
when the first bolus of chyme enters the duodenum
56
what is triggered when the intestinal phase begins?
intestinal motility pancreatic secretions bile secretion intestinal enzyme secretion