ch 20 and 21 lymphatic system and immunity Flashcards
3 functions of the lymph system
A. Drains extra interstitial fluid (1%) prevents edema (swelling)
B. Absorbs/transports dietary lipids = lacteals in small intestine
C. Involved in the immune response (chapter 21)
lacteals in what organ
small intestine
lymph vessel flow
- lymph capillaries
- lymph “collecting” vessels
- lymph trunks
- lymph ducts
lymph capillaries
smallest closed ended (example is a lacteal in small intestine
lymph “collecting” vessels
contains lymph nodes
lymph ducts
largest that empty into subclavian veins
right lymph duct
drains right head, neck, arm and trunk
left lymph duct
both legs - drains everything else.
bulge = cisternae chyli
primary lymph organs
red bone marrow and thymus gland
red bone marrow
site of RBC maturation
thymus gland
site of T cell maturation
thymus gland hormone
thymosin that targets T cells and action is maturation of T cell
secondary lymph organs
lymph nodes
spleen
tonsils
payers patch
lymph nodes
filters lymph and traps pathogens
lymph nodes cortex
outer region contains nodules and lymphocytes
lymph nodes medulla
inner region contains macrophages
spleen
largest lymph organ
tonsils
immune response in respiratory system “traps” pathogen
peyers patch
immune response in small intestine “traps” pathogens
first line of innate immunity defense
physical and chemical mechanisms
physical machnisms
skin, mucus membranes, cilia, hair, saliva, vomitting, diarrhea, urine and lacrimal
chemical mechanisms
sebum (oil), lysozyme, gastric juice and vaginal secretions
second line of innate immunity defense
antimicrobial substances
natural killer cells
phagocytes
inflammation
fever
antimicrobial substances
interferon
complement system
transferrin
complement system
20 or so proteins
interferon
neighboring cells
transferrin
transports Fe to liver
natural killer cells
non specific lymphocytes to fight tumors
phagocytes
neutrophils and monocytes
inflammation
red, heat, swell, and pain = contain infection
fever
pyrogen chemicals to hypothalamus = raise temp
antigens
anything that provokes an immune response
antigens chemical nature
large proteins, not metals or plastics
antigens genetic recombination
results in increase diversity of antibodies
major histocompatibility complex
self markers not on blood
cell mediated immunity is what type of cells
T cells
CMI (T cells) differentiation
CD4+, CD8+ and memory cells
CD4+
helper T cells
CD8+
cytotoxic T cells
memory cells
secondary response
antibody immunity is what type of cells
B cells
AMI (B cells) differentiation
plasma cells
antibody shape
Y shape with 2 light and heavy chains
AMI plasma cells
produce antibodies (neutralize, immobilize, and opsonization) for phagocytes
opsonization
makes tasty
natural active immunity
natural antigen exposure = sneeze
natural passive immunity
natural antibodies = moms milk
artificial active immunity
shot of antigens = vaccine
artificial passive immunity
shot of antibodies = anti- venom
A. Drains extra interstitial fluid (1%) prevents edema (swelling)
B. Absorbs/transports dietary lipids = lacteals in small intestine
C. Involved in the immune response (chapter 21)
3 functions of the lymph system
small intestine
lacteals in what organ
- lymph capillaries
- lymph “collecting” vessels
- lymph trunks
- lymph ducts
lymph vessel flow
smallest closed ended (example is a lacteal in small intestine
lymph capillaries
contains lymph nodes
lymph “collecting” vessels
largest that empty into subclavian veins
lymph ducts
drains right head, neck, arm and trunk
right lymph duct
both legs - drains everything else.
bulge = cisternae chyli
left lymph duct
red bone marrow and thymus gland
primary lymph organs
site of RBC maturation
red bone marrow
site of T cell maturation
thymus gland
thymosin that targets T cells and action is maturation of T cell
thymus gland hormone
lymph nodes
spleen
tonsils
payers patch
secondary lymph organs
filters lymph and traps pathogens
lymph nodes
outer region contains nodules and lymphocytes
lymph nodes cortex
inner region contains macrophages
lymph nodes medulla
largest lymph organ
spleen
immune response in respiratory system “traps” pathogen
tonsils
immune response in small intestine “traps” pathogens
peyers patch
physical and chemical mechanisms
first line of innate immunity defense
skin, mucus membranes, cilia, hair, saliva, vomitting, diarrhea, urine and lacrimal
physical machnisms
sebum (oil), lysozyme, gastric juice and vaginal secretions
chemical mechanisms
antimicrobial substances
natural killer cells
phagocytes
inflammation
fever
second line of innate immunity defense
interferon
complement system
transferrin
antimicrobial substances
20 or so proteins
complement system
neighboring cells
interferon
transports Fe to liver
transferrin
non specific lymphocytes to fight tumors
natural killer cells
neutrophils and monocytes
phagocytes
red, heat, swell, and pain = contain infection
inflammation
pyrogen chemicals to hypothalamus = raise temp
fever
anything that provokes an immune response
antigens
large proteins, not metals or plastics
antigens chemical nature
results in increase diversity of antibodies
antigens genetic recombination
self markers not on blood
major histocompatibility complex
T cells
cell mediated immunity is what type of cells
CD4+, CD8+ and memory cells
CMI (T cells) differentiation
helper T cells
CD4+
cytotoxic T cells
CD8+
secondary response
memory cells
B cells
antibody immunity is what type of cells
plasma cells
AMI (B cells) differentiation
Y shape with 2 light and heavy chains
antibody shape
produce antibodies (neutralize, immobilize, and opsonization) for phagocytes
AMI plasma cells
makes tasty
opsonization
natural antigen exposure = sneeze
natural active immunity
natural antibodies = moms milk
natural passive immunity
shot of antigens = vaccine
artificial active immunity