ch 20 and 21 lymphatic system and immunity Flashcards
3 functions of the lymph system
A. Drains extra interstitial fluid (1%) prevents edema (swelling)
B. Absorbs/transports dietary lipids = lacteals in small intestine
C. Involved in the immune response (chapter 21)
lacteals in what organ
small intestine
lymph vessel flow
- lymph capillaries
- lymph “collecting” vessels
- lymph trunks
- lymph ducts
lymph capillaries
smallest closed ended (example is a lacteal in small intestine
lymph “collecting” vessels
contains lymph nodes
lymph ducts
largest that empty into subclavian veins
right lymph duct
drains right head, neck, arm and trunk
left lymph duct
both legs - drains everything else.
bulge = cisternae chyli
primary lymph organs
red bone marrow and thymus gland
red bone marrow
site of RBC maturation
thymus gland
site of T cell maturation
thymus gland hormone
thymosin that targets T cells and action is maturation of T cell
secondary lymph organs
lymph nodes
spleen
tonsils
payers patch
lymph nodes
filters lymph and traps pathogens
lymph nodes cortex
outer region contains nodules and lymphocytes
lymph nodes medulla
inner region contains macrophages
spleen
largest lymph organ
tonsils
immune response in respiratory system “traps” pathogen
peyers patch
immune response in small intestine “traps” pathogens
first line of innate immunity defense
physical and chemical mechanisms
physical machnisms
skin, mucus membranes, cilia, hair, saliva, vomitting, diarrhea, urine and lacrimal
chemical mechanisms
sebum (oil), lysozyme, gastric juice and vaginal secretions
second line of innate immunity defense
antimicrobial substances
natural killer cells
phagocytes
inflammation
fever
antimicrobial substances
interferon
complement system
transferrin
complement system
20 or so proteins
interferon
neighboring cells
transferrin
transports Fe to liver
natural killer cells
non specific lymphocytes to fight tumors
phagocytes
neutrophils and monocytes
inflammation
red, heat, swell, and pain = contain infection
fever
pyrogen chemicals to hypothalamus = raise temp
antigens
anything that provokes an immune response
antigens chemical nature
large proteins, not metals or plastics
antigens genetic recombination
results in increase diversity of antibodies
major histocompatibility complex
self markers not on blood
cell mediated immunity is what type of cells
T cells
CMI (T cells) differentiation
CD4+, CD8+ and memory cells
CD4+
helper T cells
CD8+
cytotoxic T cells