Ch. 2 Approaches in Psychopathology Flashcards
current thinking of psychopathology
- integrative and multifaceted
- interdisciplinary focus
- informed by clinicians and researchers
- no one offers the “best” conceptualization; each informs causes and treatment
- cause and treatment is uniquely social unlike medical practices such as Cardiovascular Surgery
genetic influences
- to some degree, all behavior is heritable
- behaviorists wanted to learn about the consequences of behavior among the environments
- genes are not in isolation from environment
- environments shape how genes are expressed AND
- genes shape the environment
- relationship between genes and environment is bidirectional
genes
piece of the whole DNA within chromosome
gene expression
whether or not we physically express info on genes
polygenic
multiple genes are involved and contribute
heritability
extent to which trait is transmitted genetically
epigenetics
everything but genetic code that influence gene expression
- on and off switch
ex. stress response
shared environment
income, child-rearing practices, marital status, and quality
nonshared environment
unique to each family member
behavioral genetics
study of the degree to which genes and environments influence behavior
- how much do genes and environments influence
- genotype vs. phenotype
genotype
having a gene for a particular trait or disorder
ex. having gene for breast cancer, but not getting it based on an environmental factor
phenotype
what is seen; what manifests
molecular genetics
identifies functions of genes
- identifies differences in sequence and structures of genes between people
- alleles
- polymorphism
alleles
different form of the same gene
polymorphism
a single difference in DNA on a gene occurring in a particular population
single nucleotide polymorphisms
difference between people in a single nucleotide in the DNA sequence of a particular gene
- SNPs
copy number variations
abnormal copy of one or more sections of DNA within the gene
- differences in gene structure
- additions or deletions
genome-wide association studies
- key method to examine SNPs and CNVs
- SNPs are tools
- can identify variations within a population of a single gene sequence
- isolate difference between those with and without disorder
- psychological disorders involve many genes
- Brainstorm Consortium international study
gene-environment interaction
sensitivity to environmental event is influenced by genes
ex. stress; how long and short your fuse is and how long and short a burn is coming back to normal level
- epigenetics
epigenetics
studies how environments can alter genetic expression or function
- animal studies show that epigenetic effects transmit generationally
ex. Rwanda Genocides → stress hormone crosses into utero, DNA methylation causes dysregulated stress response
- look Quasi-experimentally
challenges of genetic influences
- genes and environments are reciprocally related
the same genes can react differently in the same environment - this relationships is incredibly complex
what does consciousness allow us to do? Remember and approach our goals while being able to make adjustments to environmental changes - genetic vulnerability increases risk broadly for multiple disorders
diagnostic model is based on symptoms but medicine uses an etiology approach (looks at cause)
neuroscience influences
- neurons and neurotransmitters
- structure-function relationships
- autonomic nervous system
- neuroendocrine system
- immune system
neuron
- a single nerve cell
- the unit of neural communication
- soma, dendrite, axon, terminal button
soma
cell body that contains nucleus
dendrite
receivers of neuron messages
axon
long, processes coming out of soma
-mylin aids speeding the process of messages up
terminal button
place where receiving neuron becomes sending neurons
synapse
small gap between two neurons where the nerve signal passes electrically or chemically from the axon of the first to the dendrites, cell body, or axon of the second
golgi apparatus
packages neurotransmitters into vesicles and releases them that attach to begin at the soma
neurontransmitters
chemical substances important in transferring a nerve impulse from one neuron to another; messages
- merge with presynaptic membrane; postsynaptic membrane picks them up