Ch 18: Female Reproductive System: Vulva and Vagina

Question 1

Adenosis associated malignant proliferation which can be a complication of in utero DES exposure

Answer 1

clear cell adenocarcinoma

Question 2

Infection of fallopian tube cells by N. gonorrhea can lead to 1_____. Complications of this include 2._____ and ____. Another, more systemic complication of N. gonorrhea infection affecting joints is 3._____

Answer 2

1. acute salpingitis
2. tubo-ovarian abscess and PID
3. septic arthritis

Question 3

Five histological characteristics of cells in extramammary Paget disease are

Answer 3

1. vacuolated cytoplasm
2. abundant glycosaminoglycans
3. staining with PAS
4. staining with mucicarmine
5. CEA (+)

Question 4

This condition is characterized by white plaques, atrophic skin, hyperkeratosis, loss of rete ridges, and a homogenous, acellular zone in the upper dermis

Answer 4

Lichen Sclerosus

Question 5

Lichen Sclerosus is associated what category of disorders?

Answer 5

Autoimmune disease

Question 6

The infectious agent associated with condyloma acuminatum is 1.____ while the infectious agent associated with condylomata lata, also known as 2._____, is 3.______

Answer 6

1. Human papillomavirus (usually types 6 & 11)
2. syphilitic warts
3. Treponema chlamydia (Syphilis)

Question 7

The second stage of this disease is characterized by bilateral inguinal lymph node enlargement. Suppurative fistulas may also develop. The third stage can involve elephantiasis and rectal strictures. What disease is it and what is the infectious agent?

Answer 7

Chlamydia infection

Chlamydia trachomatis

Question 8

Histological characteristics of Chlamydia infection include

Answer 8

inclusion or coccoid bodies
necrotizing granulomas
neutrophilic infiltrate

Question 9

Chancroid or painful sores on the genitalia with vesiculopustular lesions and granulomatous inflammation are characteristic of infection by

Answer 9

Haemophilus ducreyi

Question 10

One complication of Haemophilus ducreyi infection is

Answer 10

urethral stenosis

Question 11

Well differentiated squamous cell carcinomas which often show keratin pearls, commonly express

Answer 11

cytokeratins

Question 12

When vaginal discharge from this gram negative coccobacilli is mixed with 10% KOH it develops a “fishy odor”

Answer 12

Gardnerella vaginalis

Question 13

Bartholin glands are found on the 1.____. Blocking their drainage produces a 2.____ which can lead to formation of an 3._____

Answer 13

1. Vulva
2. Bartholin cyst
3. abscess

Question 14

Staphylococcus aureus colinization of the vagina can lead to 1.______ from production of a immune modifying toxin

Answer 14

Toxic shock syndrome

Question 15

Toxic shock syndrome is associated with use of long acting _____

Answer 15

tampons

Question 16

Two major complications of toxic shock syndrome are

Answer 16

shock

disseminated intravascular coagulation