ch 11 salivary pathology (just diseases) Flashcards
Mucocele or mucus cyst
-salivary duct cyst
Ranula
-mucocele on the floor of the mouth
Sialolithiasis
- most often ductal system of submandibular gland
- major gland sialoliths cause episodic swelling esp at mealtime
Sialadenitis
- infectious and non-inf causes
- affected gland swollen,
- low grade fever
Kuttner tumor
Sialadenitis in submand. G. persistent enlargement
Chronic sclerosing sialadentits
sialadenitis with fibrous present
Rare inflammatory condition of minor salivary glands
- lower lip with swelling and eversion as result of hypertrophy and inflammation of glands,
- middle aged and older men
Cheilitis Glandularis
The openings of the minor glands are inflamed and dilated and pressure on the glands may produce mucopurulent secretions
cheilitis glandularis
excessive salivation
sialorrhea
dry mouth
xerostomia
- mikulicz disease vs syndrome
- epimyoepithelial islands
- malt lymphomas
- now thought MD probably sjogren syndrome
Benign lymphepithelial lesion
-chronic, systemic autoimmune disease that principally involves the salivary and lacrimal glands resulting in xerostomia and xerophthalmia (dry eyes)
Sjorgren Syndrome
-possibly also known as Sicca syndrome
effect of sjorgren’s syndrom on the eye(s)
Keratoconjunctivitis sicca (sicca Syndrome)
“fruit-laden branchless tree”
sjogrens syndrome
- noninflammatory disorder; salivary gland enlargement (parotids)
- endocrine, nutritional or neurogenic
- conditions include DM, general malnutrition, alcoholism and bulimia
- caused by deregulation of autonomic innervation of salivary acini with excessive accumulation of secretory granules (enlargement)
Sialadenosis (Sialosis)
- locally destructive inflammatory condition of salivary glands
- ischemia leads to local infarction
- predisposing factors include: trauma, injections, ill-fitting dentures, URI, adjacent tumors and previous surgery
- -posterior palate
Necrotizing Sialometaplasia
-Most common Salivary Gland neoplasm
Pleomorphic Adenoma (pleomorphic multiple forms of the supportive stroma, it’s not what makes the tumor, it’s the surrounding stuff)
tumor that is exclusively parotid
-huge male predillection, especially in smokers
Warthin tumor
canalicular and basal cell types; some feel warthin tumor and oncocytoma should be included
- CA exclusively minor glands in upper lip followed by BM; BCA mostly parotid followed by UL
- surgical excision
- same tumor as pleomorphic adenmoa, but no stroma
Monomorphic adenoma(s)
-most common malignant Salivary Gland neoplasm;
-occurs faily evenly over wide age range,
most common malignant SGT in CHILDREN
MUCOEPIDERMOID CARCINOMA
- Bc of distinctive histological features originally called cylindroma
- 50% develop in minor glands and rare in parotid….
- most common middle aged adults and rare younger than 20
- tendency to show PERINEURAL invasion (and metastasis) which probably corresponds to the clinical finding of pain
- histo shows cribriform tubular and solid variants
- sometimes cells have a swirling arrangement around nerve bundles
- Persistent tumor
- the histology looks like “cylinders” or swiss cheese
Adenoid cystic Carcinoma
- exclusively a tumor of minor salivary glands
- 65% hard or soft palate followed by UL and BM
- 2/3 of all cases in females
- painless mass that may have been present for a long time with slow growth
- perineural invasion but prognosis is good
Polymorphous low-grade Adenocarcinoma