Ch. 11 (Isotonic and Buffer solutions)

Question 1

Simple Isotonic solutions formula

Answer 1

0.52 x molecular weight / 1.86 x dissociation (i) = g of solute / 1000 g of H2O

Question 2

Equivalent tonic effect to NaCl

Answer 2

g x E-value = g, equivalent tonic effect to NaCl

Question 3

Molecular wt of NaCl / i factor of NaCl x i factor of substance / molecular wt of substance = NaCl equivalent (E)

Answer 3

Sodium Chloride Equivalent

Question 4

g ( drug substance ) x E-value (drug substance) / 0.009 = ml H2O

Answer 4

Preparing Isotonic solution by Volume Adjustment

Question 5

1% NaCl / x% NaCl = 0.58C / C needed to lower freezing point to -0.52C (0.52C is the #C that’s given)

Answer 5

Freezing point depression method