Ch 11 Corticosteroids

Question 0

Flunisolide brand name?

Answer 0

Aerospan

Question 1

Clinical indications for use of inhaled corticosteroids?

Answer 1

• maintenance or control therapy for chronic asthma
• COPD
• management of seasonal and perineal allergic/nonallergic rhinitis

Question 2

Beclomethasone dipropionate brand name?

Answer 2

QVAR
HFA gives 50-60% lung deposition
CFC gives 10-15%

Question 3

Budesonide brand names?

Answer 3

Pulmicort turbohaler/ respules

Question 5

Mometasone furoate brand name?

Answer 5

Asmanex Twisthaler
once daily
4 years and up

Question 5

Fluticasone brand name?

Answer 5

Flovent

Question 6

Ciclesonide brand name?

Answer 6

Alvesco

Question 7

Fluticasone and Salmeterol combination brand name?

Answer 7

Advair

Question 8

Budesonide and Formoterol combination brand name?

Answer 8

Symbicort

Question 10

Mometasone and Formoterol combination brand name?

Answer 10

Dulera

Question 11

What causes early phase asthma?

Answer 11

IgE

Question 12

What causes late phase asthma?

Answer 12

Mast cell mediators and release of cytokines

Question 13

Two modes of action for corticosteroids

Answer 13

1) induce gene expression for antiinflammatory proteins and receptors
2) suppress gene expression for proinflammatory proteins