CESTODES Flashcards
PLATYHELMINTHES
Classes:
Cestoda
Trematoda
Morphology:
1. [?], segmented, generally flattened [?]
2. No [?]
3. Food is absorbed by the [?]
Elongated, ribbon-like; dorsoventrically
alimentary tract and vascular system
cuticle
Parts:
Scolex
Neck
Strobila
The segments are either:
Craspedote
Acraspedote
Apolytic
Anapolytic
: proglottids overlap
Craspedote
: proglottids don’t overlap
Acraspedote
: segments are detached with mature eggs
Apolytic
: proglottids are shed when they are exhausted of eggs
Anapolytic
Excretory system has
flame cell/protonephridium
Reproductive System (most cestodes are [?] and exhibit [?])
MONOECIOUS
protandry
Vas deferens and vagina have common genital pores that may open on the following:
a. Ventral surface with uterine pore (D. latum)
b. Lateral: same side of proglottids (Hymenolepis species)
c. Lateral: irregularly alternate (Taenia spp)
d. Bilateral: 2 sets of reproductive organs are present (D. caninum)
a. Ventral surface with uterine pore
(D. latum)
b. Lateral: same side of proglottids
(Hymenolepis species)
c. Lateral: irregularly alternate
(Taenia spp)
d. Bilateral: 2 sets of reproductive organs are present
(D. caninum)
- male copulatory organ
CIRRUS
Male uterus
a. Coiled
b. Secular
c. Tube or straight
Gravid uterus
a. Reticular with ova in capsules (D. caninum)
b. With lateral branches (Taenia spp)
a. Reticular with ova in capsules
(D. caninum)
b. With lateral branches
(Taenia spp)
TWO MAIN CLASSES OF LARVA:
- Solid
- Vesicular or bladder or cystic
- Solid
- Vesicular or bladder or cystic
a. Procercoid - 2nd larval stage; bears 6 hooks near the posterior end
b. Plerocercoid - 3rd larval stage; has a solid body with a developing scolex & strobila
a. Cysticercoid - has a solid body with an invaginated scolex with poorly developed bladder or no bladder
b. Cysticercus or the true bladder - has a fluid-filled and fully developed bladder Variations:
Coenerus - has a well-developed cyst with multiple invaginated scolices from the germinal layer
Echinococcus/ hydatid cyst - has a well-developed cyst with brood capsules and daughter cells with multiple scolices
- 2nd larval stage
Proercoid
bears 6 hooks near the posterior end
a. Procercoid
- 3rd larval stage
has a solid body with a developing scolex & strobila
b. Plerocercoid
- has a solid body with an invaginated scolex with poorly developed bladder or no bladder
a. Cysticercoid
- has a fluid-filled and fully developed bladder
b. Cysticercus or the true bladder
b. Cysticercus or the true bladder Variations:
Coenerus
Echinococcus/ hydatid cyst
- has a well-developed cyst with multiple invaginated scolices from the germinal layer
Coenerus
- has a well-developed cyst with brood capsules and daughter cells with multiple scolices
Echinococcus/ hydatid cyst
Almond shape, with 2 sucking grooves or bothria
Scolex Pseudophyllidean
Genital pore Pseudophyllidean
Center of the segment
Uterine pore Pseudophyllidean
Center of the segment
Uterus Pseudophyllidean
Coiled
Ova Pseudophyllidean
Operculated, immature when laid
Oncosphere Pseudophyllidean
Ciliated and called coracidium
Larval forms Pseudophyllidean
Solid
a. Procercoid
b. Plerocercoid
Example Pseudophyllidean
Scolex Cyclophyllidean
with 4 muscular suckers
Genital pore Cyclophyllidean
Margins of segment
Uterine pore Cyclophyllidean
None
Uterus Cyclophyllidean
Sac-like; branched, eggs in capsule
Ova Cyclophyllidean
Non-operculated, mature when laid
Oncosphere Cyclophyllidean
Non-ciliated but with 3 pairs of hooks and called hexacanth embryo
Larval forms Cyclophyllidean
Cystic
a. cysticercoids
b. cysticercus
c. coenurus
d. hydatid
Example Cyclophyllidean
Diphyllobothrium latum
Fish tapeworm/Broad tapeworm
Diphyllobothrium latum
Infective stage to man: plerocercoid larva
Diphyllobothrium latum
cosmopolitan but prevalent in temperate zone where fresh water fish forms integral part of the diet (Europe, lake region of Switzerland, North America, Asia)
Diphyllobothrium latum
• 1st IH: copepods of Genus Cyclops and Diaptomus
Diphyllobothrium latum
• 2nd IH: Fresh water fishes like pike, salmon, trout, white fish
Diphyllobothrium latum
• Reservoir hosts: dogs and cats
Diphyllobothrium latum
• Final Host: man
Diphyllobothrium latum
Ova/Eggs ➢ 30-50 μm
Diphyllobothrium latum
Ova/Eggs ➢ Single shelled, broadly ovoidal with the Posterior part thickened and with operculum at one end.
Diphyllobothrium latum
Ova/Eggs ➢ Yellowish to yellowbrown in color
Diphyllobothrium latum
Ova/Eggs ➢ Immature if found in feces
Diphyllobothrium latum
Ova/Eggs ➢ 100,000 eggs/day
Diphyllobothrium latum
Coracidium ➢ liberated from eggshell
Diphyllobothrium latum
Coracidium ➢ ciliated
Diphyllobothrium latum
➢ swims freely in the water
Diphyllobothrium latum Coracidium
Procercoid larvae ➢ measures 550 in length
Diphyllobothrium latum
Procercoid larvae ➢ with 3 pairs of hooklets
Diphyllobothrium latum
Plerocercoid larvae/sparganum ➢ Measures 6 mm in length
Diphyllobothrium latum
Plerocercoid larvae/sparganum ➢ Glistening, opaque white
Diphyllobothrium latum
Plerocercoid larvae/sparganum ➢ Unsegmented and has an invaginated anterior end
Diphyllobothrium latum
Plerocercoid larvae/sparganum ➢ No scolex
Diphyllobothrium latum
Adult ➢ Largest tapeworm of man
Diphyllobothrium latum
Adult ➢ Measures 3-10 mm in length with as many as 3, 000 proglottids
Diphyllobothrium latum
Adult ➢ Ivory white in color
Diphyllobothrium latum
Scolex ➢ Almond shaped, unarmed and has 2 deep dorsoventral suctorial grooves
Diphyllobothrium latum
Proglottids ➢ Mature segment is broader than long
Diphyllobothrium latum
Diphyllobothriasis, Fish or Broad tapeworm infection, Bothriocephaliasis
Diphyllobothrium latum
➢ Systemic toxemia
Diphyllobothrium latum
➢ Mechanical obstruction of the intestines
Diphyllobothrium latum
➢ Bothriocephalus anemia of Tapeworm pernicious anemia
Diphyllobothrium latum
Macrocytic normochromic anemia; with thrombocytopenia ; mild leukopenia
Diphyllobothrium latum
➢ Intense local inflammation and eosinophilia x
Diphyllobothrium latum
➢ Human sparganosis
Diphyllobothrium latum
➢ Ocular sparganosis
Diphyllobothrium latum
– intense pain,irritation and edematous swelling of the eye lids
➢ Ocular sparganosis
- Examination of eggs and proglottids in feces
Diphyllobothrium latum
- Kato thick smear preparation
Diphyllobothrium latum
- Concentration technique
Diphyllobothrium latum
- Surgical removal of the worms and drainage of the involved sites ( Human sparganosis)
Diphyllobothrium latum
Freezing (-18oC) for 24 hours or (-10oC) for 48 hours
Diphyllobothrium latum
Fish reservoirs should be kept free of raw sewage
Diphyllobothrium latum
Boiling and filtering of drinking water
Diphyllobothrium latum
De-worming of reservoir hosts
Diphyllobothrium latum
Thorough cooking of freshwater fishes
Diphyllobothrium latum
In endemic areas, feces should not be discarded into rivers and lakes
Diphyllobothrium latum
Praziquantel (5-10 mg/kg single dose)- Drug of choice
Diphyllobothrium latum
- Drug of choice
Praziquantel (5-10 mg/kg single dose)
Niclosamide or Quinacrine hydrochloride
Diphyllobothrium latum
- used to kill adult D. latum
Niclosamide or Quinacrine hydrochloride
Paramomycine
Diphyllobothrium latum
40% ethyl alcohol with Procaine
Diphyllobothrium latum
injected into the lesion to kill plerocercoid
40% ethyl alcohol with Procaine
pork tapeworm
Taenia solium
beef tapeworm
Taenia saginata
Asian Taenia
Taenia saginata asiatica
Dwarf Tapeworm
Hymenolepis nana
Rat Tapeworm
Hymenolepis diminuta
Double-Pored Tapeworm/ Dog TW
Dipylidium caninum
Intermediate host: pig, man
Taenia solium
Definitive host: man
Taenia solium
Intermediate host: cow
Taenia saginata
Definitive host: man
Taenia saginata
Intermediate host: pig, cattle, goats, wild boars, monkeys
Taiwan taenia
Intermediate host: fleas, rice and flour beetles (Tenebrio spp)
Hymenolepis nana
Definitive host: man, rats, mice ✓ Rats: H. nana var. fraternal
Hymenolepis nana
Accidental host: Human
Hymenolepis diminuta
Dipylidium caninum
Requires intermediate host
Hymenolepis diminuta
Ova/Eggs ✓ brown, spherical
Taenia solium
Taenia saginata
Ova/Eggs ✓ 31-35 microns in diameter
Taenia solium
Taenia saginata
Ova/Eggs ✓ with 2 radially striated shells
Taenia solium
Taenia saginata
Scolex ✓ globular with 4 suckers
Taenia solium
Scolex ✓ armed with rostellum (circular tow of hooks)
Taenia solium
Proglottid ✓ 5 x 10 mm in size
Taenia solium
Proglottid ✓ with 800-1000 proglottids
Taenia solium
Gravid proglottid ✓ contains 30,000-50,000 eggs
Taenia solium
Gravid proglottid ✓ uterus exhibit 7-12 lateral branching
Taenia solium
Adult ✓ whitish, opaque in color
Taenia saginata
Adult ✓ 5 to 10 meters in length
Taenia saginata
Adult ✓ each gravid proglottid contains 80,000 eggs
Taenia saginata
• Life cycle of T. saginata: same as T. solium except for the
intermediate host
Scolex ✓ with sunken rostellum, 2 rows of hooklets
Taenia saginata asiatica
Adult Scolex ✓ unarmed
Taiwan taenia
Ovum ✓ 45 µm in diameter; 4-8 “polar filaments”
Hymenolepis nana
Ovum ✓ Size: 30-55 µm
Hymenolepis nana
Ovum ✓ Oncosphere: six hooks (seen as dark lines at 8 o’clock)
Hymenolepis nana
Larva (Cysticercoid) ✓ Tailed structure w/invaginated scolex
Hymenolepis nana
Larva (Cysticercoid) ✓ Lacks a fluid filled bladder
Hymenolepis nana
Larva (Cysticercoid) ✓ Develops in insect or human villi (SI)
Hymenolepis nana
Adults ✓ Small, L: 15-50 mm
Hymenolepis nana