Cervical Cancer

Question 1

CHEMOTHERAPY REGIMENS FOR RECURRENT OR METASTATIC CERVICAL CANCER
First-line combination therapy

Answer 1

• Cisplatin/paclitaxel/bevacizumab(category 1)
• Cisplatin/paclitaxel (category 1)
• Topotecan/paclitaxel/bevacizumab(category 1)
• Carboplatin/paclitaxel (Category 1 for patients who have received prior cisplatin therapy)
• Carboplatin/paclitaxel/bevacizumab
• Cisplatin/topotecan
• Topotecan/paclitaxel
• Cisplatin/gemcitabine (category 3)

Question 2

CHEMOTHERAPY REGIMENS FOR RECURRENT OR METASTATIC CERVICAL CANCER
Possible first line single agent therapy

Answer 2

Cisplatin (preferred as a single agent)
Carboplatin
Paclitaxel

Question 3

CHEMOTHERAPY REGIMENS FOR RECURRENT OR METASTATIC CERVICAL CANCER
Second line therapy

Answer 3

Agents listed are category 2B unless otherwise noted) 
• Bevacizumab 
• Albumin-bound paclitaxel  
• Docetaxel 
• 5-FU (5-fluorouracil) 
• Gemcitabine 
• Ifosfamide 
• Irinotecan 
• Mitomycin 
• Pemetrexed 
• Topotecan 
• Vinorelbine