Cerebral Cortex Flashcards
Layer 2
External granular layer Intracortical connections (not association though)
Layer 1
Molecular layer
Mostly synapses
Layer 3
External pyramidal layer
Association/commisural efferents
Layer 4
Internal granular layer
Thalamic afferents
Layer 5
Internal pyramidal layer
Motor efferents
Layer 6
Multiform layer
Efferents
What cell type predominates in the sensory cortex
Granular GABA
Big layer 4 where neurones terminate
What cell type predominates motor cortex
Pyramidal
Excitatory use glutamate
Describe allocortex
10% of cortex
3 layers only
Hippocampus and olfactory
What are betz cells
Giant pyramidal neurones
In 5th layer
Forms axons of corticospinal tract
Locus coeruleus afferent to subcortical areas
Uses NA
Decreased leads to depression
Brainstem raphe nuc subcortical afferent
Decreased 5-ht leads to insomnia and schizophrenia
Median forebrain complex subcortical afferent
Ach afferents,
Decreased associated with memory loss of in alzheimers
How does pet scanning work?
Radionuclear tracer attached to glucose and intravenously injected
Tracer emits gamma waves which are detected
Used simultaneously with ct scanning