Cerebellum and Basal Ganglia Flashcards

1
Q

T/F all of the efferent outflow from the basal ganglia is inhibitory.

A

True

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2
Q

All efferent neurons from the basal ganglia are found in what two areas

A

Globus Pallidus

Substantia nigra par reticularis

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3
Q

Outflow from the Globus pallidus is directed where?

A

Thalamic nuclei

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4
Q

Outflow from the Globus pallidus is has what effect on the thalamus

A

suppresses stimulation from the thalamus to the motor centers

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5
Q

Outflow from the substantia nigra is directed where?

A

Superior Colliculus

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6
Q

Lessens the efferent outflow from the basal ganglia to the motor cortex

A

Direct pathway

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7
Q

Strengthens the efferent outflow from the basal ganglia to the motor cortex

A

Indirect pathway

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8
Q

Inhibitory neurons in the striatum are stimulated by ____

A

Cortical inputs

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9
Q

Provides selective disinhibition of thalamocortical circuits

A

direct pathway

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10
Q

___ receptors strengthen the responsiveness of neurons that feed into the direct pathway

A

D1 receptors

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11
Q

___ receptors lessens the responsiveness of neurons that feed into the indirect pathway

A

D2 receptors

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12
Q

Dopaminergic neurons within the basal ganglia serve to modulate the responsiveness of ______ nerurons to cortical inputs

A

striatal neurons

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13
Q

Important in initiation of a movement plan and motor learning

A

Basal ganglia

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14
Q

The Cerebellum receives what kind of information

A

senorimotor information from the cerebral cortex and

peripheral sensory information reporting on movement

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15
Q

Information from the cerebrum to the cerebellum flow through what two nuclei

A

Pontine nuclei

inferior olive

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16
Q

What kind of information doe the cerebellum get from the spinocerebellum

A

somatosensory and proprioceptive information

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17
Q

Vestibular information goes from the vestibular nuclei to the cerebellum via ____

A

Vestibulocerebellum

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18
Q

The efferents from the cerebellar cortex project to what two nuclei

A

Deep cerebellar nuclei and to the vestibular nuclei

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19
Q

Tract that contributes to motor planning by projecting to the pre-motor cortex

A

Cerebrocerebellum

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20
Q

Tract that contributes to motor execution by projecting to motor cortex and brain stem

A

spinocerebellum

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21
Q

Tract that projects to the vestibulocerebellumm to contribute to balance and vestiubulo-ocular reflex

A

Vestibulocerebellum

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22
Q

Where does integration and processing of inputs take place in the cerebellum

A

Cerebellar cortex

23
Q

Information to the Cerebellum Feeds into _____ which carry efferent signal out from the cortex

A

Purkinje cells

24
Q

Efferent outflow from purkinje cells is ____ to neurons with in the deep nuclie

A

inhibitory

25
Purkinje cells project in what plane
Sagittal
26
Input is fed into the purkinje cells via what two ways
Climbing fibers or granule cell projections
27
Granule cells receive excitatory inputs from what kind of fibers?
Mossy fibers
28
Granule cells project to what cells
Purkinje cells
29
Mossy fibers originate from where
pontine nuclei
30
Mossy fibers carry what kind of information to purkinje cells
sensorimotor and motor plan information from the cerebral cortex Sensory information from spinal cord and vestibular nuclei
31
Climbing fibers originate from where?
inferior olivary nucleus
32
Climbing fibers carry what kind of information to purkinje cells
information form cerebral cortex, reticular formation and spinal cord
33
Responsiveness of purkinje cells to mossy fibers is modulated by what two inhibitory interneurons
stellate cells and basket cells
34
Inhibitory interneuron that projects across a row of purkinje cells
basket cells
35
Inhibitory interneuron that projects in all directions but is more focused on a localized group of purkinje cells
Stellate cells
36
Modulate the the frequency of the long trains of action potentials from purkinje cells
Mossy fibers
37
Interrupt the steady frequency generated by purkinje cells by adding complex spikes
Climbing fibers
38
Mossy and climbing fibers inputs are modulated through ____ cirucuits
Recurrent loop circuits
39
Modulate mossy fiber inputs by creating a recurrent loop with granule cells
golgi cells
40
Modulate climbing fiber inputs by creating a recurrent loop with the inferior olivary nucleus
deep cerebellar nuclie that releases inhibitory GABA
41
Cerebrocerebellum recieves input from the cerebral cortext through ____ nuclei
Pontine nuclei
42
Output from the cerebrocerebellum ges through the _____ nucleus
Dentate nucleus
43
From the dentate nucleus, axons are sent to two locations
Contralateral ventrolateral thalamus | Contralateral red nucleus
44
_____ provides corrective control over body and limb movements
spinocerebellum
45
Tract that sends a copy of the information sent to the effector muscles, to the spinocerebellum during motion
Ventral spinocerebellar tract
46
Tract that reports to the spinocerebellum about muscle and joint receptors, regardless of activity
Dorsal spinocerebellar tract
47
The spinocerebellum takes information from ____ and ____ tracts and compares the inputs to make corrections during movements
Ventral and dorsal spinocerebellar tracts
48
Control eye movements and coordinate movement of the head and eyes
Medial vestibular nucleus
49
Control axial muscles and limb extensors to maintain balance
Lateral vestibular nucleus
50
What kind of cerebellar fibers are associated with motor learning
Climbing fibers
51
In cases of cerebellar disease what are the three deficits that can arise
Hypertonia ataxia intention tremor
52
Diminished resistance to passive limb displacement (over shooting, excessive rebound)
Hypertonia
53
delay in initiation of movement; errors in range and force
Ataxia
54
Errors in position, especially at the end of movements
Intention tremor