Cerebellum Flashcards

1
Q

What are the main functions of the cerebellum?

A

Motor functions (coordination, precision and timing of movement) as well as motor memory, language, higher level processing and some personality aspects

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2
Q

What embryonic division is the cerebellum part of?

A

Metencephalon (which is a subdivision of the rhombencephalon/ hindbrain)

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3
Q

Where is the cerebellum found?

A

Posterior cranial fossa
Inferior to occipital and temporal lobes
Separated from the pons by the fourth ventricle

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4
Q

What is the anatomical structure of the cerebellum?

A

Two hemispheres connected by the vermis

Divided into grey matter (forms the cerebellar cortex) and white matter (containing four nuclei)

Three lobes - anterior, posterior and flocculonodular - separated by two fissures - primary and posterolateral

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5
Q

What are the three functional zones of the cerebellum?

A

Cerebrocerebellum (planning movements and motor learning)

Spinocerebellum (regulation of body movements and input of proprioceptive information)

Vestibulocerebellum (control of balance and ocular reflexes)

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6
Q

What is the blood supply to the cerebellum?

A

Posterior inferior cerebellar artery (PICA)

Anterior inferior cerebellar artery (AICA)

Superior cerebellar artery

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7
Q

What is the venous drainage of the cerebellar?

A

Superior and inferior cerebellar veins - drain into the superior petrosal, transverse and straight dural venous sinuses

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8
Q

What can cause cerebellar dysfunction?

A

Stroke
Trauma
Tumours
Chronic excess alcohol use

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9
Q

What symptoms can be caused by damage to the cerebellum?

A
Dysdiadochokinesia 
Ataxia
Nystagmus 
Intention tremor
Scanning speech 
Hypotonia
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10
Q

What tests can be done to assess cerebellum function?

A

Finger to nose
Heel to shin
Hand flip

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11
Q

Will motor cerebellum symptoms normally present as ipsilateral or contralateral?

A

Ipsilateral

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12
Q

What is the tentorium cerebelli?

A

Dural fold protecting the cerebellum from being squashed by the rest of the brain and to prevent movement

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13
Q

What part of the cerebellum is commonly damaged by chronic alcoholism or a medulloblastoma?

A

Anterior lobe

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14
Q

What signs or symptoms would you expect to see from a midline cerebellum lesion (e.g. vermis?

A

Truncal Ataxia

Dysarthria (difficult or unclear articulation of speech)

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15
Q

What signs and symptoms would you expect to see from a lesion to the cerebellar hemispheres (lateral cerebellar structures)?

A
Dysdiadochokinesia 
Intention tremor 
Loss of balance
Dysmetria ("overreach" caused by inability to judge distances) 
Rebound phenomena
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16
Q

What are the output cells of the cerebellar and are they excitatory or inhibitory?

A

Purkinje cells - inhibitory (GABAergic)