Cerebellum Flashcards

1
Q

In order to accomplish the functions of the cerebellum, the cerebellum must have (2 things)

A
  1. reciprocal interactions with motor regions of the CNS

2. integration with sensation with motor signals

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2
Q

T/F

a cerebellar lesion of loss of function leads to a paralysis or loss of sensation

A

FALSE

It leads to an inability to move in a smooth and coordinated manner

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3
Q

What are two non motor functions of the cerebellum?

A

Cognitive functions: memory, language, visual spatial processing

Emotional Regulation: affect, behavioral regulation and mood

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4
Q

What are the three lobes of the cerebellum?

What is each lobe associated with?

A

Anterior-spinal cord input-proprioceptive input
Posterior-cortex
Flocculonodular- vestibular input

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5
Q

T/F Output from the Cerebellum to other CNS structures can come from the deep nuclei, OR the cortex of the cerebellum.

A

False!!!
Output can only come from deep nuclei,

Input can go to either the cortex of the cerebellum OR the nuclei

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6
Q

T/F The inferior and middle peduncles of the cerebellum are pathways for afferent information

A

True.
Inferior and middle=input
superior=output

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7
Q

The spinocerebellar pathways project from _____ peduncle, to which two lobes of the cerebellum

A

Inferior peduncle

anterior and posterior lobes

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8
Q

T/F vestibular inputs to the cerebellum come directly from the vestibular receptors ONLY.

A

False.

Directly from receptors AND indirectly from vestibular nuclei

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9
Q

What information is gathered from vestibular inputs?

A

Head position in space

status of extensor motor neurons

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10
Q

Which cerebellar lobes does the reticular formation project to?

A

Vermal regions of the anterior and posterior lobe

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11
Q

T/F The reticular projections provide integrated information from the cortex and cord

A

True:

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12
Q

What type of infomation comes from the reticular formation to the cerebellum?

A

Mediates extensor tone

coordination of movement, balance, and equilibrium

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13
Q

Tectal projections to the cerebellum give us what infomration?

A

Visual and auditory input

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14
Q

Trigeminal nucleus to the cerebellum gives us what information

A

proprioceptive info of the face

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15
Q

What are the three types of internal fibers?

A

Mossy
Climbing
Purkinje

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16
Q

These fibers provide sensory and motor input; arise from all inputs except those from inferior olive

A

Mossy fiber

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17
Q

This fiber type provides output from the cerebellar cortex. They drive specific movements

A

Purkinje fiber

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18
Q

This fiber projects from the inferior olive; synapses on purkinje cells

A

Climbing fiber

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19
Q

This fiber is thought to be responsible for guiding encoding of new stimulus-response links

A

Climbing fiber

20
Q

This fiber gets outputting information from the cerebellar nuclei

21
Q

These two fibers receive inputting information

A

Mossy and climbing fibers

22
Q

What are the three layers of the cerebellar tissue?

A

Granular
Molecular
Purkinje

23
Q

What are the two types of cerebellar cells?

A

Interneurons (granular, golgi, stellate)

Purkinje cells

24
Q

This cell receives output from cerebellar cortex and is inhibitory

A

Purkinje cells

25
This fiber is excitatory and receives widespread input from the cord, reticular formation, vestibular system and pons
Mossy fiber
26
This fiber projects to deep cerebellar nuclei and granule cells
Mossy fibers
27
This fiber receives diverse input and keeps record of ongoing activity constantly. It provides background information
Mossy fiber
28
This fiber is associated with efferent monitory "corollary discharge"
Mossy fiber
29
This fiber is excitatory and receives input from the inferior olive
Climbing fiber
30
This fiber projects to deep cerebellar nuclei and purkinje cells at a 1:1 ratio
Climbing fiber
31
This fiber receives cortical input involved in the programming and execution of intended movement
climbing fiber
32
Which output influences eye and postural movements and plays a role in equilibruim contral
Vestibulocerebellar
33
T/F vestibulocerebellar efferent pathways connect with vestibular nuclei reicprocally
True
34
Vestibular nuclei send information to the flocculonodular lobe of the cerebellum which gives input to which deep nucleus
Fastigial Which then sends input back to the vestibular nuclei
35
Which two nuclei make up the interposed nucleus?
Globose and Emboliform
36
Trace the input pathway from cortical input to the interposed nucleus
Red nucleus->interior olive->anterior/posterior lobe_> interposed nucleus
37
T/F Interposed nuclei mediate cervical flexors
True
38
This nucleus is triggered by sensory cues in the environment. Signals direction of movement and joint position and relays information to motor cortex to adjust timing, intensity and velocity
Dentate nucleus
39
Where does the dentate nucleus recieve input from?
Cortical input-> pontine nucleus-->cerebellar hemispheres==> dentate nucleus
40
Where does the dentate nucleus send information?
VL thalamus-->motor cortex
41
Ataxia is a observable issue with which part of the cerebellum?
Floculonodular lobe | and vermal region of the anterior or posterior lobe
42
Ataxia is characterized by what movements?
Wide, slow gait | Tendency to fall toward side of lesion
43
Hypotonia may be an observation of problems in which part of the cerebellum?
Vermal or paravermal region We don't really fuckin' know.
44
Dysarthria and cerebellar nystagmus is associated with issues in which part of the cerebellum?
Vermal lesions
45
The inferior olive recieves input from which two things?
Red nuclues "cortico-rubro-olivary fibers (sensorimotor) And Spinal cord fibers
46
From the inferior olive, trace the infomration pathway
Inferior peduncle spinocerebellar fibers go to anterior lobe cerebrocerebellar fibers go to posterior lobe