cephalosporins Flashcards

1
Q

cefazolin

A

ancef

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2
Q

cephalexin

A

keflex

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3
Q

cefadroxil

A

duricef

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4
Q

Examples of 1st generation cephalosporins

A

cefazolin, cephalexin, cafadroxil

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5
Q

purpose of cephalosporin

A

good positive activiity and limited gram negative

poor CSF penetration

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6
Q

spectrum of activity for 1st gen cephalosporin

A

staphylococcus spp.
s.pyogenes (group A strep)
s. agalactiae (group B strep)
viridian’s group strep
PCNs susceptible s.pneumoniae

NO MRSA, MRSE, enterococci spp. and L.monocytogenes

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7
Q

Cephalexin’s activity is poor against

A

s.pneumoniae ( became resistant)
CoNS ( became resistant)

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8
Q

1st gen cephalorsporin GN coverage

A

PEK
P. mirabilis
e.coli
k.pneumoniae

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9
Q

1st gen cephalorsporin anaerobes coverage

A

bacteroids (not b.fragilis)
clostridium (excludes c.diff)
peptostreptococcus
prevotella
fusbacterium
cutibacterium

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10
Q

cefaclor

A

ceclor

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11
Q

cefuroxime

A

ceftin , zinacef

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12
Q

cefoxitin*

A

mofoxin

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13
Q

cefprozil

A

cefzil

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14
Q

2nd gen cephalosporins purpose

A

too groups true cephalosporins and cepamycins with enhanced GN

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15
Q

Spectrum of activity of for cephalosporins , GP

A

less staph
staphylococcus spp.
s.pyogenes (group A strep)
s. agalactiae (group B strep)
viridian’s group strep
PCNs susceptible s.pneumoniae

NO MRSA, MRSE, enterococci spp. and L.monocytogenes

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16
Q

Spectrum of activity of for cephalosporins , GN

A

enhanced

HNPEKM
h.influenzaie
neisseria
p.mirabolis
e.coli
k.pnemoniae
m.catarrhil

17
Q

Spectrum of activity of for cephalosporins , anaerobes

A

clostirum spp.
peptostreptoccous spp.
bacteroids spp
provotella spp
funsobacterium spp

18
Q

does cefoxitin and cefeton

A

borreliea burgdorferi

19
Q

Spectrum of activity of for cephalosporins CSF

A

non

20
Q

Spectrum of activity of for cephalosporins , SE

A

pCNs
GI N/V/D
disulfiram reactions and coagulupathies (MTT side chain)

21
Q
A